AI Article Synopsis
- - The study aimed to evaluate how common cardiovascular risk factors (CVRFs) are in patients with acute unilateral inner ear hypofunction (AUIEH) and their effects, focusing on conditions like acute unilateral peripheral vestibulopathy (AUPVP) and sudden sensorineural hearing loss (SSNHL).
- - Researchers analyzed data from 125 patients and 250 control participants, finding that patients had significantly higher rates of CVRFs like high blood pressure, diabetes, and dyslipidemia, with an increased risk for AUIEH linked to having two or more CVRFs.
- - The conclusion suggests that patients with AUIEH have a notably higher prevalence of CVRFs, and underscores the need for
Article Abstract
Objectives: To assess the prevalence of cardiovascular risk factors (CVRFs) and their impact on acute unilateral inner ear hypofunction (AUIEH), including acute unilateral peripheral vestibulopathy (AUPVP), sudden sensorineural hearing loss (SSNHL) and acute unilateral audiovestibular hypofunction (AUAVH).
Methods: One hundred and twenty-five patients consecutively diagnosed with AUPVP, SSNHL or AUAVH and 250 sex- and age-matched controls were included. Cases presented a mean age of 58.6 ± 14.7 years and included 59 women and 66 men. The correlation between CVRFs (high blood pressure [HBP], diabetes mellitus [DM], dyslipidemia [DLP], cardiocerebrovascular disease [CCVD]) and AUIEH was assessed by multivariate conditional logistic regression analysis.
Results: A higher prevalence of CVRFs was identified in patients than in controls (30 individuals with DM, 53 with HBP, 45 with DLP and 14 with a previous history of CCVD, < .05). A significantly elevated risk of AUIEH was found in patients with two or more CVRFs (adjusted odds ratio [OR] 5.11; 95% CI 2.23-11.70). Previous CCVD individually predicted AUIEH (OR 8.41; 95% CI 2.36-29.88). Subgroup analysis showed the same tendency for AUPVP and SSNHL.
Conclusion: Acute unilateral inner ear hypofunction patients presented significantly more CVRFs than controls, and the presence of two or more CVRFs was associated with AUIEH. Future studies evaluating vascular risk in AUIEH may include AUPVP and SSNHL patients from the same source population to better characterize risk profiles that can indicate a vascular origin.
Level Of Evidence: 3b.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948582 | PMC |
| http://dx.doi.org/10.1002/lio2.992 | DOI Listing |
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