Analyzing time-dependent data acquired in a continuous flow is a major challenge for various fields, such as big data and machine learning. Being able to analyze a large volume of data from various sources, such as sensors, networks, and the internet, is essential for improving the efficiency of our society's production processes. Additionally, this vast amount of data is collected dynamically in a continuous stream. The goal of this research is to provide a comprehensive framework for forecasting big data streams from Internet of Things networks and serve as a guide for designing and deploying other third-party solutions. Hence, a new framework for time series forecasting in a big data streaming scenario, using data collected from Internet of Things networks, is presented. This framework comprises of five main modules: Internet of Things network design and deployment, big data streaming architecture, stream data modeling method, big data forecasting method, and a comprehensive real-world application scenario, consisting of a physical Internet of Things network feeding the big data streaming architecture, being the linear regression the algorithm used for illustrative purposes. Comparison with other frameworks reveals that this is the first framework that incorporates and integrates all the aforementioned modules.
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http://dx.doi.org/10.1007/s11227-023-05100-x | DOI Listing |
Crit Care
January 2025
Department of Neuro-Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Background And Objectives: Antibody-negative autoimmune encephalitis (AE) is a form of encephalitis characterized by the absence of detectable autoimmune antibodies, despite immunological evidence. However, data on management of patients with antibody-negative AE in the intensive care unit (ICU) are limited. This study aimed to explore the characteristics and subtypes of antibody-negative AE, assess the effects of immunotherapy, and identify factors independently associated with poor functional outcomes in patients requiring intensive care.
View Article and Find Full Text PDFJ Pediatr Endocrinol Metab
January 2025
Department of Endocrinology, Genetics and Metabolism, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Objectives: To develop a clinical model for predicting the occurrence of Central Precocious Puberty based on the breast development outcomes in chinese girls.
Methods: This is a retrospective study, which included a total of 1,001 girls aged 6-9 years old who visited the outpatient clinic of Beijing Children's Hospital from January 2017 to October 2022 for "breast development". Participants were categorized into pubertal development (PD) cohort and simple premature breast development (PT) according to the criteria, and information was collected and tested for relevant indicators.
J Mol Neurosci
January 2025
Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Alzheimer's disease (AD) is a neurodegenerative disease with no effective treatment, often preceded by mild cognitive impairment (MCI). Multimodal imaging genetics integrates imaging and genetic data to gain a deeper understanding of disease progression and individual variations. This study focuses on exploring the mechanisms that drive the transition from normal cognition to MCI and ultimately to AD.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong, China.
Alzheimer's Disease (AD) significantly aggravates human dignity and quality of life. While newly approved amyloid immunotherapy has been reported, effective AD drugs remain to be identified. Here, we propose a novel AI-driven drug-repurposing method, DeepDrug, to identify a lead combination of approved drugs to treat AD patients.
View Article and Find Full Text PDFSci Rep
January 2025
Renewable Energy Research Group, Isfahan, Iran.
The performance of nanofluids is largely determined by their thermophysical properties. Optimizing these properties can significantly enhance nanofluid performance. This study introduces a hybrid strategy based on computational intelligence to determine the optimal conditions for ternary hybrid nanofluids.
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