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| http://dx.doi.org/10.3389/fcvm.2023.1151064 | DOI Listing |
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Editorial: COVID-19 and the central nervous system: Emerging insights from experimental neurology.
Exp Neurol
January 2025
Department of Neurology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan. Electronic address:
Management of renin-angiotensin system inhibitors prior to major surgery: insights from the STOP-or-NOT trial.
Br J Anaesth
December 2024
INI-CRCT Network, Nancy, France; Université Paris Cité, AP-HP, Hôpital Lariboisière, DMU PARABOL, Service d'Anesthésie-réanimation-CTB, Paris, France; UMR-942 "MASCOT", Inserm, Paris, France.
Strong recommendations on how to manage renin-angiotensin system inhibitors, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, before surgery are lacking because of a lack of evidence, which is mostly limited to data from observational studies. The STOP-or-NOT trial was a large multicentre randomised trial designed to determine whether chronic renin-angiotensin system inhibitors should be continued or discontinued before major noncardiac surgery. As principal investigators of the STOP-or-NOT trial, we discuss the trial's results and how they contribute to the existing literature on management of renin-angiotensin system inhibitors before surgery.
View Article and Find Full Text PDFThe selective sorting of miR-4432 into endothelial extracellular vesicles is controlled by a specific RNA binding protein: New Insights in the pathophysiology of venous malformations.
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Department of Artificial Intelligence and Informatics, Mayo Clinic, Jacksonville, FL, United States.
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