AI Article Synopsis
- Prosthetic joint infections are serious but rare, causing significant emotional and economic burdens on patients and healthcare systems.
- The study investigated how four bacterial species adhere to two different alloys (Ti6Al4V and CoCrMo) commonly used in joint prostheses by analyzing surface characteristics like topography and roughness.
- Results showed that CoCrMo promoted more bacterial aggregation and reduced bacterial viability compared to Ti6Al4V, suggesting that chemical composition plays a crucial role in bacterial adhesion despite similar physical surface properties.
Article Abstract
Prosthetic joint infection is an uncommon entity, but it supposes high costs, both from the economic side to the health systems and from the emotional side of the patient. The evaluation of the bacterial adherence to different materials frequently involved in joint prostheses allows us to better understand the mechanisms underlying this and provide information for the future development of prevention strategies. This study evaluated the bacterial adherence of four different species (, , and ) on Ti6Al4V and CoCrMo. The topography, surface contact angles, and linear average roughness were measured in the samples from both alloys. The interaction with the surface of both alloys was significantly different, with the CoCrMo showing an aggregating effect on all the species, with additional anti-adherent activity in the case of . The viability also changes, with a significant decrease ( < 0.05) in the CoCrMo alloy. In the case of the viability in the supernatant from the samples was different, too, with a decrease in the colony-forming units in the Ti6Al4V, which could be related to cation release from the surface. Beyond adhesion is a multifactorial and complex process, and considering that topography and wettability were similar, the chemical composition could play a main role in the different properties observed.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959577 | PMC |
| http://dx.doi.org/10.3390/ma16041505 | DOI Listing |
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