BPA is a plasticizer for the production of polycarbonate plastics and epoxy resins and is widely used in the production of household goods, including food packaging. Free BPA is known to migrate from packaging to food, and its uptake has been associated with adverse health effect, particularly the disruption of endocrine activity. The presence and migration of BPA from plastic consumer products are subject to strict regulation in the EU. The aim of this study is to analyse the migration of BPA from different packaging items and household products sold on the Croatian market. To simulate real life exposure, we treated samples with a food simulant. The analytical performance was confirmed with the EU requirements. BPA levels were assessed in 61 samples by HPLC-FLD and the LOQ of the method was 0.005 mg kg for the food simulant. These results showed that the levels of BPA that migrated to the food simulant were below LOQ and in accordance with the specific migration limit into food, which was defined as 0.05 mg kg for all samples. None of the analysed products presented a health hazard. However, these regulations do not refer to products intended for children's use, in which BPA is banned. Furthermore, regulations require testing before putting products on the market, and previous research shows that possible BPA migration occurs due to various uses, along with a cumulative effect of exposure from even very small concentrations. Therefore, for accurate BPA consumer exposure evaluation and possible health risks, a comprehensive approach is needed.
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http://dx.doi.org/10.3390/ijerph20042877 | DOI Listing |
Cytotechnology
February 2025
Thoracic Surgery Department, The Second Affiliated Hospital of Kunming Medical University, Kunming, 650101 Yunnan China.
Unlabelled: The chemical substance bisphenol A (BPA) is widely used in household products, and its effect on human health has frequently been the focus of research. The aim of this study was to explore the potential molecular regulatory mechanism of BPA on the proliferation and migration of lung cancer cells. In this study, the H1299 and A549 lung cancer cell lines were selected as the study objects.
View Article and Find Full Text PDFTalanta
December 2024
Department of Chemistry & Institute for Sustainable Energy, College of Sciences, Shanghai University, Shanghai, 200444, PR China. Electronic address:
Bisphenols, as common industrial raw materials, are widely used in food packaging such as plastics. However, their migration and residue may affect the hormone secretion of the human body and then lead to health problems. Therefore, a low-cost, rapid and simple detection method that can simultaneously detect multiple bisphenols is very necessary.
View Article and Find Full Text PDFWater Res
February 2025
Key Laboratory of Water Cycle & Related Land Surface Processes, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Northeast China as an important base of grain production in China, has been suffering from potential groundwater pollution due to the excessive and prolonged application of fertilizers and pesticides. However, exploration of emerging contaminants pollution in groundwater and assessment of human health and ecological risks caused by large-scale agricultural activities have been relatively scarce. This study collected groundwater samples from typical agricultural areas in Northeast China to investigate the extent of contamination by nitrate, per- and polyfluoroalkyl substances (PFASs) and endocrine-disrupting compounds (EDCs), and then compared the levels of these pollutants with those in other regions of China.
View Article and Find Full Text PDFEnviron Toxicol
November 2024
School of Environmental and Biological Engineering, Nanjing University of Science & Technology, Nanjing, China.
The increasing incidence of cancer underscore the necessity of investigating contributors such as endocrine-disrupting chemicals (EDCs), including bisphenol A (BPA). Although BPA's risks are well-documented, comprehensive studies on its substitutes, such as bisphenol B (BPB), are limited. Dysregulated lipid metabolism is a hallmark of cancer progression.
View Article and Find Full Text PDFEnviron Monit Assess
November 2024
Department of Pure and Industrial Chemistry, Nnamdi Azikiwe University, Awka, 420007, Anambra State, Nigeria.
Bisphenol A (BPA) is a vital raw material used to manufacture various household and commercial goods. However, BPA is a contaminant of emerging concern (CEC) and an endocrine-disrupting chemical (EDC) capable of migrating and bio-accumulating in environmental and biological compartments. At threshold levels, they become toxic causing adverse health and environmental issues.
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