AI Article Synopsis
- The study evaluated the SD BIOLINE HIV/Syphilis Duo rapid diagnostic test for accuracy, acceptability, and feasibility among pregnant women, female sex workers, and men who have sex with men.
- It compared field test results with standard laboratory tests, showing 100% sensitivity and specificity for HIV and 95% sensitivity for syphilis antibody detection.
- Participants and health professionals found the test highly acceptable and easy to use, suggesting it could enhance access to rapid testing if included in health service supplies.
Article Abstract
We field-assessed the accuracy, acceptability, and feasibility of the SD BIOLINE HIV/Syphilis Duo rapid diagnostic test in three groups: pregnant women, female sex workers (FSW), and men who have sex with men (MSM). Venous blood samples collected in the field were compared with the respective gold standard methods: SD BIOLINE HIV/Syphilis Duo Treponemal Test versus FTA-abs (Wama brand) treponemal laboratory test for syphilis, and SD BIOLINE HIV/Syphilis Duo Test versus the fourth generation Genscreen Ultra HIV Ag-Ag (Bio-Rad brand) laboratory test for HIV. From a total of 529 participants, 397 (75.1%) were pregnant women, 76 (14.3%) FSW and 56 (10.6%) MSM. Sensitivity and specificity parameters of HIV were 100.0% (95% CI: 82.35-100.0%) and 100.0% (95% CI: 99.28-100.0%), respectively. Sensitivity and specificity parameters found for TP antibody detection were 95.00% (95% CI: 87.69-98.62%) and 100.0% (95% CI: 98.18-100.0%), respectively. The SD BIOLINE HIV/Syphilis Duo Test showed high acceptability among participants (85.87%) and health professionals (85.51%), as well as easy usability by professionals (91.06%). The usability of the SD BIOLINE HIV/Syphilis Duo Test kit would not be a barrier to accessing rapid testing, if the product were incorporated into the list of health service supplies.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955085 | PMC |
| http://dx.doi.org/10.3390/diagnostics13040810 | DOI Listing |
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