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Ubiquitin-proteasome pathway annotation in can reveal potential targets for RNAi-based pest management. | LitMetric

AI Article Synopsis

  • Ubiquitination is a process that marks proteins for degradation by the proteasome and is regulated by ATP.
  • Researchers annotated 15 genes from the ubiquitin-proteasome pathway in the Asian citrus psyllid, an insect that plays a key role in spreading the harmful bacterium Liberibacter asiaticus, which causes citrus greening disease.
  • Understanding these genes' roles and how they are affected by the bacterium can help develop RNA interference strategies to manage the spread of this disease in citrus crops.

Article Abstract

Ubiquitination is an ATP-dependent process that targets proteins for degradation by the proteasome. Here, we annotated 15 genes from the ubiquitin-proteasome pathway in the Asian citrus psyllid, . This psyllid vector has come to prominence in the last decade owing to its role in the transmission of the devastating bacterial pathogen, Liberibacter asiaticus (Las). Infection of citrus crops by this pathogen causes Huanglongbing (HLB), or citrus greening disease, and results in the eventual death of citrus trees. The identification and correct annotation of these genes in will be useful for functional genomic studies to aid the development of RNAi-based management strategies aimed at reducing the spread of HLB. Investigating the effects of Las infection on the expression of ubiquitin-proteasome pathway genes may provide new information about the role these genes play in the acquisition and transmission of Las by .

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933519PMC
http://dx.doi.org/10.46471/gigabyte.43DOI Listing

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