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Characterization of glucagon-like peptide-1 (GLP-1) agonist exposures reported to a single United States poison center.
Clin Toxicol (Phila)
January 2025
Rocky Mountain Poison and Drug Safety Center, Denver, CO, USA.
Introduction: Glucagon-like peptide-1 agonists have gained attention in recent years due to their efficacy in managing type II diabetes mellitus and their emerging role in weight management. The purpose of this study was to characterize glucagon-like peptide-1 agonist exposures reported to a single United States regional poison center over nine years, including causes of exposure, associated clinical effects, and potential areas for improving patient education and safety.
Methods: This retrospective cohort study analyzed all poison center calls involving glucagon-like peptide-1 agonists submitted to a single United States regional poison center from 14 January 2014 to 1 May 2023.
Artificial Intelligence in Nephrology: Clinical Applications and Challenges.
Kidney Med
January 2025
Division of Nephrology, Florida State University School of Medicine, Tallahassee, FL.
Artificial intelligence (AI) is increasingly used in many medical specialties. However, nephrology has lagged in adopting and incorporating machine learning techniques. Nephrology is well positioned to capitalize on the benefits of AI.
View Article and Find Full Text PDFPractical Considerations for the rapid titration of VNS.
Epilepsy Behav Rep
March 2025
Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
For patients with drug-resistant epilepsy who are not candidates for epilepsy surgery, Vagus nerve stimulation (VNS) is the most widely available neuromodulation option and has been available in several countries for 30 years. Given its broad availability and extended history on the market, many healthcare providers (HCPs) have developed individualized practice habits regarding the titration and dosing of VNS. This study provides novel evidence to describe the extent to which VNS management differs among providers and discusses recent literature that indicates how unique programming approaches may impact patient outcomes.
View Article and Find Full Text PDFAdvances in intraoperative imaging in retinal diseases: A narrative review.
Taiwan J Ophthalmol
December 2024
Department of Ophthalmology, Londrina State University, Londrina, Paraná, Brazil.
This review explores recent technological advances in intraoperative imaging during retinal disease surgeries, focusing on their applicability in clinical practice and impact on surgical outcomes. A literature search identified studies discussing new imaging technologies, their advantages over conventional methods, relevant case studies, and literature reviews. Exclusion criteria included studies unrelated to retinal diseases, imaging technologies not suitable for intraoperative use, outdated articles, and nonscientific reports.
View Article and Find Full Text PDFCurrent advances in multimodal imaging in geographic atrophy secondary to age-related macular degeneration: A review.
Taiwan J Ophthalmol
November 2024
Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia.
As we move toward an era in which there will be treatment options for geographic atrophy (GA) secondary to age-related macular degeneration, the need to accurately understand and interpret multimodal imaging (MMI) for the condition is paramount. This review discusses the evolution of MMI in GA and how it has led to a greater understanding of different phenotypes and risk factors for progression. These advancements have allowed novel imaging biomarkers to be used as end points in large interventional studies exploring new therapies for GA treatment.
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