AI Article Synopsis

  • Acute myeloid leukemia (AML) can occur outside the bone marrow during diagnosis or relapse, sometimes affecting areas like the uterine cervix.
  • Granulocytic sarcoma in the uterine cervix is a rare condition, with no standard treatment available.
  • Two cases of limited AML relapse in the cervix demonstrated that combining brachytherapy with chemotherapy may be an effective and well-tolerated treatment option.

Article Abstract

Acute myeloid leukemia (AML) may extend to extra-medullary sites at diagnosis or at relapse, either isolated or associated with bone marrow disease. Granulocytic sarcoma of uterine cervix is rare, and there is no established treatment for this disease. Two cases of uterine cervix-limited AML relapse showed that brachytherapy may be an effective therapeutic option in this setting along with chemotherapy, with good tolerance.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924153PMC
http://dx.doi.org/10.5114/jcb.2022.123980DOI Listing

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