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Herbal Supplement-Induced Liver Injury: A Case Report. | LitMetric

Herbal Supplement-Induced Liver Injury: A Case Report.

Cureus

Internal Medicine, Icahn School of Medicine at Mount Sinai, Elmhurst Hospital Center, Elmhurst, USA.

Published: January 2023

AI Article Synopsis

Article Abstract

We present the case of a 45-year-old woman who arrived at the emergency department complaining of sudden epigastric pain. An inpatient evaluation revealed no evidence of viral or immunologic infection. Additionally, imaging did not elicit a clear cause for the patient's symptoms. Further examination revealed that the patient had recently begun using a herbal tea and that symptoms had completely resolved after discontinuation. Though rare, hepatotoxicity secondary to herbal supplement ingestion, or herbal supplement-induced liver injury, or HILI, should be considered in all patients presenting with abnormal liver function tests.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928137PMC
http://dx.doi.org/10.7759/cureus.33663DOI Listing

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Article Synopsis
  • * Samples of HDS consumed by patients were analyzed using high-performance liquid chromatography-mass spectrometry (HPLC-MS) to verify the presence of both botanical and non-botanical ingredients.
  • * Results showed that in 37% of cases, chemical analysis led to higher likelihood scores for DILI attribution, indicating it enhances confidence in diagnosing such injuries from HDS, though further research is necessary to fully integrate this method into clinical practice.
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Herbal and dietary supplements (HDS) are a common etiology of drug induced liver injury and, specifically, Herbalife® supplements have been implicated. Hepatitis associated aplastic anemia (HAAA) is a rare and potentially fatal complication after acute hepatitis characterized by pancytopenia. While there have been rare cases of HDS leading to HAAA, no cases of Herbalife® induced liver injury leading to HAAA have been reported from this specific HDS.

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