Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in western countries. The association between CLL and glomerular disease (GD) is rare. The most frequent GD associated with CLL is membranoproliferative membranous glomerulonephritis (GN) (MPGN) (45%) types I and II, followed by membranous glomerulonephritis, with the same reports of immunotactoid glomerulopathy (ITG). We report a case of ITG diagnosed on kidney biopsy in a CLL patient and the response of renal parameters to drug treatment for CLL. The patient was treated with several lines of therapies with a good response.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928648 | PMC |
http://dx.doi.org/10.1002/jha2.592 | DOI Listing |
Nephrology (Carlton)
January 2025
Department of Nephrology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Immunotactoid glomerulopathy (ITG), a condition characterised by highly organised microtubules on electron microscopy, and cryoglobulin glomerulopathy (CG) are rare forms of kidney injury that may be encountered in patients with cryoglobulinaemia. It has been proposed these two entities are part of the same disease process following observed clinical and histological similarities.
View Article and Find Full Text PDFIntern Med
October 2024
Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Japan.
Nephrology (Carlton)
November 2024
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
Cureus
July 2024
Nephrology, University of Florida College of Medicine, Jacksonville, USA.
Immunotactoid glomerulopathy (ITG) is a rare form of glomerular disease. It is characterized by organized, dense immunoglobulin deposits in the glomerulus, impairing glomerular function and filtration. The prognosis tends to be poor, and the majority of patients develop end-stage renal disease (ESRD).
View Article and Find Full Text PDFAdv Kidney Dis Health
July 2024
Department of Medicine, Section of Nephrology, University of Chicago, Chicago, IL. Electronic address:
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