Purpose: To assess the magnitude of differences between attenuation values of the true non-contrast image (TNC) and virtual non-contrast image (VNC) derived from twin-beam dual-energy CT (tbDECT) and dual-source DECT (dsDECT).
Materials And Methods: This retrospective study included 62 patients who underwent liver dynamic DECT with tbDECT ( = 32) or dsDECT ( = 30). Arterial VNC (AVNC), portal VNC (PVNC), and delayed VNC (DVNC) were reconstructed using multiphasic DECT. Attenuation values of multiple intra-abdominal organs ( = 11) on TNCs were subsequently compared to those on multiphasic VNCs. Further, we investigated the percentage of cases with an absolute difference between TNC and VNC of ≤ 10 Hounsfield units (HU).
Results: For the mean attenuation values of TNC and VNC, 33 items for each DECT were compared according to the multiphasic VNCs and organs. More than half of the comparison items for each DECT showed significant differences (tbDECT 17/33; dsDECT 19/33; Bonferroni correction < 0.0167). The percentage of cases with an absolute difference ≤ 10 HU was 56.7%, 69.2%, and 78.6% in AVNC, PVNC, and DVNC in tbDECT, respectively, and 70.5%, 78%, and 78% in dsDECT, respectively.
Conclusion: VNCs derived from the two DECTs were insufficient to replace TNCs because of the considerable difference in attenuation values.
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http://dx.doi.org/10.3348/jksr.2021.0193 | DOI Listing |
Sci Rep
January 2025
Physics Department, Faculty of Science, Fayoum University, Fayoum, Egypt.
For the purpose of this study, four natural rock samples-namely, diorite, granodiorite, tonalite, and granite-are being investigated about their radiation attenuation. The elemental composition of the rocks was obtained through Energy dispersive X-ray spectroscopy (EDX) which examines the microstructural and localized area elemental analyses of the four rock samples. A Monte Carlo simulation (MCNP) was used to determine and evaluate the investigated samples.
View Article and Find Full Text PDFClin Radiol
November 2024
Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Rd., Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China. Electronic address:
Aim: To investigate the relationship between epicardial adipose tissue (EAT) and myocardial strain and the severity of coronary artery disease (CAD), and to evaluate the predictive value of EAT parameters in early left ventricular (LV) diastolic dysfunction.
Materials And Methods: One hundred seventy patients with suspected CAD who underwent both coronary computed tomography angiography and echocardiography were enrolled in 2020. LV global strains were calculated using commercial software.
J Nat Med
January 2025
Department of Endocrinology, Cangzhou Central Hospital, No. 16 West Xinhua Road, Cangzhou, 061000, Hebei, China.
Thioredoxin-interacting protein (TXNIP), as a pivotal protein in the cellular stress response, plays a significant role in the progression of diabetic nephropathy (DN). Consequently, therapeutic strategies aimed at targeting TXNIP may offer novel interventions for patients with DN. Our study is to explore the therapeutic potential of targeting TXNIP in mitigating renal tubular injury induced by hyperglycemia.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Bristol, Bristol, United Kingdom.
Background: Homeostatic sleep regulation is theorized to be governed by the 'Two Process Model' where circadian rhythm (process C) and homeostatic sleep pressure (process S) interact to determine sleep versus wakefulness. Sleep pressure accumulated during prolonged wakefulness increases the duration and intensity of subsequent 'recovery' sleep. Multiple sleep abnormalities are associated with Alzheimer's Disease (AD) Dementia and Lewy Body Dementia (LBD).
View Article and Find Full Text PDFClin Endocrinol (Oxf)
January 2025
Gulhane Faculty of Medicine, Department of Endocrinology and Metabolism, University of Health Sciences, Ankara, Turkey.
Objective: Patients with mild autonomous cortisol secretion (MACS) are at increased risk of cardiometabolic outcomes, such as hyperglycemia, metabolic syndrome, and cardiovascular diseases. Nonalcoholic fatty liver disease (NAFLD) is also associated with increased cardiometabolic risk. We aimed to investigate the prevalence and predictors of NAFLD in metabolically healthy subjects with MACS.
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