Adult-onset immunodeficiency due to interferon-γ-neutralizing autoantibodies (nIFNγ-autoAbs) can remain underdiagnosed. We present a case of severe infection with nIFNγ-autoAbs. To ensure early diagnosis, clinicians should have a high index of suspicion in patients of Asian descent with opportunistic infections and perform QuantiFERON-TB assay for disease screening.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929714PMC
http://dx.doi.org/10.1093/ofid/ofad035DOI Listing

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