Drawing on both mathematical and anthropological understandings of fractality, this paper explores alternative perspectives of time as it relates to heroin addiction and poly-substance use in Scotland. The paper ethnographically illustrates temporalities which confound typical conceptualizations of linearity, and which can be better understood as fractal. Senses of linear time are disrupted for people who use heroin through intensive poly-substance use, an increasing trend in Scotland, as both time and memory become fragmented beyond coherence or re-assemblage. Distortedness and complexity being common descriptors applied to mathematical fractals, time shattered into uncountable and un-interpretable fragments similarly connotes fracture, dissonance, and distortion. A meaningful engagement with fractal theory contains the potential to open up new vocabulary, imagery, and theoretical avenues with which to grasp complex and non-linear time experience. The aims of the paper are, therefore, twofold; to both provide a nuanced ethnographic exploration of substance use time, and to develop a reflexive analytical framework for temporal experience through fractals.
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http://dx.doi.org/10.3389/fpsyt.2023.1116142 | DOI Listing |
Climacteric
January 2025
Department of Gynecology and Obstetrics, Guizhou Provincial People's Hospital, Guiyang, China.
Objective: For patients with contraindications to hormone therapy, the absence of effective treatments for ovarian dysfunction post chemotherapy represents a critical issue requiring resolution. Local administration of mitochondria may enhance ovarian function in premature ovarian insufficiency (POI) by ameliorating diminished mitochondrial activity. Nevertheless, there is a paucity of literature on the efficacy of mitochondrial transplantation through intravenous injection, a less invasive and more convenient method than local injection, for the improvement of ovarian function in POI following chemotherapy.
View Article and Find Full Text PDFDevelopment
January 2025
Pediatric Genomics Discovery Program, Departments of Pediatrics and Genetics, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
Emerging evidence suggests that the nuclear pore complex can have unique compositions and distinct nucleoporin functions in different cells. Here, we show that Nup107, a key component of the NPC scaffold, varies in expression over development: it is expressed at higher levels in the blastula compared to the gastrula suggesting a critical role prior to gastrulation. We find depletion of Nup107 affects the differentiation of the early germ layers leading to an expansion of the ectoderm at the expense of endoderm and mesoderm.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Sree Chitra Tirunal Institute for Medical Sciences and Technology, Bioceramics Division, Biomedical Technology Wing, 695011, Thiruvananthapuram, INDIA.
A collagen-inspired helical protein-mimic has been synthesized via topochemical polymerization of a designed tripeptide monomer. In the monomer crystal, molecules arrange in a head-to-tail manner, forming supramolecular helices. The azide and alkyne of adjacent molecules in the supramolecular helix are proximally preorganized in a ready-to-react arrangement.
View Article and Find Full Text PDFCreat Nurs
January 2025
Society and Ageing Research Lab, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Educational programs for health-care providers increasingly implement culturally sensitive care. Clear methods for educating students in cultural awareness are still lacking. Research indicates that simply increasing knowledge on ethnicity, culture, or migration does not improve culturally sensitive behavior and can foster stereotypes.
View Article and Find Full Text PDFClin EEG Neurosci
January 2025
Palma Sola Neurology Associates, Bradenton, FL, USA.
Evoked potential metrics extracted from an EEG exam can provide novel sources of information regarding brain function. While the P300 occurring around 300 ms post-stimulus has been extensively investigated in relation to mild cognitive impairment (MCI), with decreased amplitude and increased latency, the P200 response has not, particularly in an oddball-stimulus paradigm. This study compares the auditory P200 amplitudes between MCI (28 patients aged 74(8)) and non-MCI, (35 aged 72(4)).
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