A new chromone derivative, aspergione A (), along with seven known metabolites, was isolated from a mangrove endophytic fungus, sp. GXNU-B1, which was collected from mangrove L. Their structures and the absolute configuration of were elucidated based on the analysis of HR-ESI-MS, NMR, and ECD calculation. Compounds - were evaluated for their anti-inflammatory effects on the production of nitricoxide (NO). Compounds and have potent inhibitory effects against NO production in activated macrophages with IC values of 38.26 and 44.30 M, respectively.
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| http://dx.doi.org/10.1080/14786419.2023.2181805 | DOI Listing |
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