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Development and evaluation of high fidelity, multidisciplinary simulation training course for high consequence infectious diseases using fluorescence visualisation.
J Hosp Infect
December 2024
Health - Exposure and Control Group, Health and Safety Executive Science and Research Centre, Buxton, UK. Electronic address:
Background: High consequence infectious diseases (HCID) include contact-transmissible viral haemorrhagic fevers and airborne-transmissible infections such as Middle Eastern Respiratory Syndrome. Assessing suspected HCID cases requires specialised infection control measures including patient isolation, personal protective equipment (PPE), and decontamination. There is need for an accessible course for NHS staff to improve confidence and competence in using HCID PPE outside specialist HCID centres.
View Article and Find Full Text PDFA faulty simulation model guided Ramanujan Digital twin architecture for rotating machine health monitoring.
ISA Trans
December 2024
State Key Laboratory of Tribology, Department of Mechanical Engineering, Tsinghua University, Beijing, PR China. Electronic address:
The conventional widely-used health monitoring methods for rotating machines have shortcomings such as the reliance on the selection of the preset parameters. Also, the strong noise interference caused by factors such as transmission path hinders the practical application of many fault feature extraction methods. To overcome these gaps, the digital twin notion is introduced and a new digital twin architecture called the Ramanujan Digital Twin (RDT) is designed.
View Article and Find Full Text PDFFast and accurate prediction of drug induced proarrhythmic risk with sex specific cardiac emulators.
NPJ Digit Med
December 2024
ELEM Biotech S.L., Pier 07, Via Laietana, 26, Barcelona, 08003, Spain.
In silico trials for drug safety assessment require many high-fidelity 3D cardiac simulations to predict drug-induced QT interval prolongation, which is often computationally prohibitive. To streamline this process, we developed sex-specific emulators for a fast prediction of QT interval, trained on a dataset of 900 simulations. Our results show significant differences between 3D and 0D single-cell models as risk levels increase, underscoring the ability of 3D modeling to capture more complex cardiac responses.
View Article and Find Full Text PDFImproved surgical skill is generally associated with improved patient outcomes, although assessment is subjective, labour intensive, and requires domain-specific expertise. Automated data-driven metrics can alleviate these difficulties, as demonstrated by existing machine learning instrument tracking models. However, these models are tested on limited datasets of laparoscopic surgery, with a focus on isolated tasks and robotic surgery.
View Article and Find Full Text PDFA Modern Education Theory Approach to Development of a Benchtop Simulation Model for Ultrasound-Guided Percutaneous Nephrolithotomy.
J Endourol
December 2024
Department of Urology, University of California San Francisco, San Francisco, California, USA.
To develop and validate a high-fidelity, nonbiohazardous simulator model for the ultrasound-guided percutaneous nephrolithotomy procedure. We employed a systematic framework based on Delphi consensus and modern education theory to design a simulation model. Twelve expert surgeons provided input through a hierarchal task analysis and identified procedural tasks, anatomical landmarks, and potential errors.
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