AI Article Synopsis

  • Gastric adenocarcinomas are significant due to their prevalence and complex biology, prompting the need for effective classification and grading systems in clinical settings.
  • This study analyzed 112 cases to assess the effectiveness and agreement of different classification methods for diagnosing these tumors.
  • Findings revealed a strong correlation between the Lauren and WHO 2019 classifications and grading systems, highlighting their practical use in diagnosing and determining treatment strategies for varying tumor aggressiveness.

Article Abstract

Gastric adenocarcinomas are lesions that raise important issues in clinical practice, due to their incidence and biological behavior. Over time, various systems have been used for classifying and grading of gastric adenocarcinomas, in the hope of increasing the diagnostic accuracy. In this study we statistically analyzed 112 cases of gastric adenocarcinomas in relation to different classification and grading systems, in order to identify their efficacy and concordance in the histopathological diagnosis. The results indicated a significant association of the Lauren and World Health Organization 2019 classifications and also between these and the three-tier and two-tier grading systems, which supports their practical utility in establishing the diagnosis and assessment of the tumor aggressiveness, for the differentiated therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940934PMC
http://dx.doi.org/10.12865/CHSJ.48.03.06DOI Listing

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