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| http://dx.doi.org/10.3389/fbioe.2023.1146729 | DOI Listing |
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A framework towards implementation of sequencing for antimicrobial-resistant and other health-care-associated pathogens.
Lancet Infect Dis
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Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Antimicrobial resistance continues to be a growing threat globally, specifically in health-care settings in which antimicrobial-resistant pathogens cause a substantial proportion of health-care-associated infections (HAIs). Next-generation sequencing (NGS) and the analysis of the data produced therein (ie, bioinformatics) represent an opportunity to enhance our capacity to address these threats. The 3rd Geneva Infection Prevention and Control Think Tank brought together experts to identify gaps, propose solutions, and set priorities for the use of NGS for HAIs and antimicrobial-resistant pathogens.
View Article and Find Full Text PDFCharacterization of Pediatric Extrathoracic Aerosol Deposition with Air-Jet Dry Powder Inhalers.
J Aerosol Sci
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Department of Mechanical and Nuclear Engineering, Virginia Commonwealth University, Richmond, VA.
The use of air-jet dry powder inhalers (DPIs) offers a number of advantages for the administration of pharmaceutical aerosols, including the ability to achieve highly efficient and potentially targeted aerosol delivery to the lungs of children using the oral or trans-nasal routes of administration. To better plan targeted lung delivery of pharmaceutical aerosols with these inhalers, more information is needed on the extrathoracic (ET) depositional loss in pediatric subjects when using relatively small (e.g.
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Front Cell Dev Biol
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Istituto di Neuroscienze, Consiglio Nazionale delle Ricerche, Pisa, Italy.
Introduction: Recent research revealed that Tau plays critical roles in various neuronal functions. We previously demonstrated that destabilization and nuclear delocalization of Tau alter the expression of glutamatergic genes, mediating early neuronal damage.
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Clinical Microbiology: where do we stand?
Front Antibiot
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Department of Public Health Policy, School of Public Health, University of West Attica, Athens, Greece.
Clinical Microbiology has developed during the last 100 years, simultaneous with the discovery of microorganisms as causes of infections. Globalization and One Health determine present needs whereas molecular biology, automation, artificial intelligence, and bioinformatics are new tools that characterize the new developments in the field.
View Article and Find Full Text PDFThe next generation of drug resistant tuberculosis drug design.
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