AI Article Synopsis
- * Traditional treatments for MetS involve multiple medications, which can lower patient compliance and raise side effects.
- * Berberine (BBR) has emerged as a promising alternative due to its effectiveness and safety, with potential benefits across various MetS-related conditions, but further clinical trials are needed.
Article Abstract
The prevalence of metabolic syndrome (MetS) is drastically growing worldwide, resulting in MetS-associated kidney disease. According to traditional theories, preventing blood pressure, lipid, glycose, and obesity and improving insulin resistance (IR), a couple of medications are required for MetS. It not only lowers patients' compliance but also elevates adverse reactions. Accordingly, we attempted to seek answers from complementary and alternative medicine. Ultimately, berberine (BBR) was chosen due to its efficacy and safety on MetS through multi-pathways and multi-targets. The effects and mechanisms of BBR on obesity, IR, diabetic nephropathy, hypertension, hyperlipidemia, and hyperuricemia were elaborated. In addition, the overall properties of BBR and interventions for various kidney diseases were also collected. However, more clinical trials are expected to further identify the beneficial effects of BBR.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939707 | PMC |
| http://dx.doi.org/10.3389/fphar.2023.1112088 | DOI Listing |
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