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The gastrointestinal (GI) tract is targeted by severe acute respiratory syndrome coronavirus-2. The present review examines GI involvement in patients with long coronavirus disease and discusses the underlying pathophysiological mechanisms that include viral persistence, mucosal and systemic immune dysregulation, microbial dysbiosis, insulin resistance, and metabolic abnormalities. Due to the complex and potentially multifactorial nature of this syndrome, rigorous clinical definitions and pathophysiology-based therapeutic approaches are warranted.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721275 | PMC |
| http://dx.doi.org/10.1016/j.gtc.2022.12.001 | DOI Listing |
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