AI Article Synopsis

  • A single nucleotide alteration (G to C) occurs in intron 1 of the HLA-C*12:02:02:01 gene.
  • This change leads to the formation of a new variant of the HLA allele, designated as HLA-C*12:02:02:22.
  • The discovery highlights how small genetic changes can create new alleles in the human genome.

Article Abstract

One nucleotide change (G > C) in intron 1 of HLA-C*12:02:02:01 results in novel HLA allele HLA-C*12:02:02:22.

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Source
http://dx.doi.org/10.1111/tan.15005DOI Listing

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