Aim: This case report describes a giant pheochromocytoma in a young female, experienced cardiac symptoms, treated by a transperitoneal laparoscopic right adrenalectomy.
Material And Methods: A 29 years old female with Taki-tsubo syndrome, consequent to the chronic release of catecholamines, with a palpable abdominal mass and vague abdominal symptoms was referred to our department. Abdominal CT scan has demonstrated a solid mass of 13 cm in the right adrenal space so, after pre-operative management with alpha-adrenergic receptor and beta blockade and a 3D CT scan reconstruction a right adrenalectomy laparoscopic approach was performed.
Results: Our result underlines that 13 cm in size for a giant pheochromocytoma is not an absolute contraindication to perform a minimally invasive approach in expert hands, with optimal surgical, oncological and cosmetic results.
Discussion: The only curative option for non-metastatic pheochromocytomas disease is surgical resection. Laparoscopic adrenalectomy is the treatment of choice but the limit size for a safe and feasible minimally invasive approach is not yet defined.
Conclusions: This case report could help to better define more solid recommendations in the next future and also provide landmarks and key steps for laparoscopic surgeons.
Key Words: Giant Pheochromocytoma, Laparoscopic Adrenalectomy, Pheochromocytoma Management.
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Discov Oncol
December 2024
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Introduction: Although giant cystic pheochromocytoma and paraganglioma (PPGL) are uncommon, they can be life-threatening when it occurs. Unfortunately, prior case reports have shown that giant cystic PPGLs are highly susceptible to diagnostic errors. Therefore, this study aimed to explore giant cystic PPGLs by comparing them with non-cystic PPGLs, defining the clinical features of the affected patients, and analyzing the characteristics of misdiagnosis and mistreatment associated with PPGLs.
View Article and Find Full Text PDFJCEM Case Rep
November 2024
Department of Urology, Kurume University School of Medicine, Kurume, Fukuoka, Japan 830-0011.
A 44-year-old man was diagnosed with a giant pheochromocytoma in the right retroperitoneal cavity following treatment for heart failure. Subsequent to improvement in cardiac function, the patient underwent a laparotomy to excise the tumor. Due to its considerable size, partial cardiopulmonary bypass and blood purification therapy were initiated to stabilize hemodynamics during the surgical intervention.
View Article and Find Full Text PDFBMC Infect Dis
October 2024
Department of Urology, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Jixi Road 218, Shushan District, Hefei, Anhui, 230022, China.
J Clin Endocrinol Metab
September 2024
Division of Endocrinology, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN, 55905, USA.
Context: Data on giant pheochromocytomas (PHEO), defined based on size ≥ 10 cm, are scarce.
Objective: to compare presentation, management, and outcomes of patients with giant vs non-giant PHEOs.
Design: retrospective cohort study, 2000-2023.
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