Electrochemical Detection of Sulfadiazine by Sensors based on Chemically Modified Carbon Electrodes: A Review.

Curr Top Med Chem

Laboratory of Molecular Spectroscopy Modelling, Materials, Nanomaterials, Water and Environment, CERNE2D, Faculty of Science, Mohammed V University in Rabat, Rabat, Morocco.

Published: August 2023

The consumption of medicines (usually pharmaceuticals and chemical health products) has increased in recent decades due to the demand for medicines for various diseases (headache, relapsing fever, dental absence, streptococcal infection, bronchitis, ear and eye infections). Instead, their overuse can lead to serious environmental damage. Sulfadiazine is one of the most often used antimicrobial medications for both human and veterinary therapy, yet its presence in the environment, even in low quantities, offers a potential concern as an emergency pollutant. It is vital to have a monitoring that's quick, selective, sensitive, stable, reversible, reproducible, and easy to use. Electrochemical techniques realizing cyclic voltammetry (CV), differential pulse voltammetry (DPV), and square wave voltammetry (SWV), using a modified electrode based on carbon as a surface modifier are an excellent option that makes control simple and quick owing to their cheap cost and convenience of use, while also safeguarding human health from drug residue buildup. This study discusses different chemically modified carbon-based electrodes such as graphene paste, screen printed electrode, glassy carbon, and boron diamond doped electrodes for SDZ (sulfadiazine) detection in various formulation feeds, pharmaceuticals, milk, and urine samples, the results obtained also show high sensitivity and selectivity with lower detection limits compared to matrix studies, which may explain its use in trace detection. Furthermore, the effectiveness of the sensors is assessed by other parameters including buffer solution, scan rate, and pH. Also, a method for real sample preparation was also discussed in addition to the different methods mentioned.

Download full-text PDF

Source
http://dx.doi.org/10.2174/1568026623666230210115740DOI Listing

Publication Analysis

Top Keywords

chemically modified
8
electrochemical detection
4
detection sulfadiazine
4
sulfadiazine sensors
4
sensors based
4
based chemically
4
modified carbon
4
carbon electrodes
4
electrodes review
4
review consumption
4

Similar Publications

Convertible Hydrogel Injection Sequentially Regulates Diabetic Periodontitis.

ACS Biomater Sci Eng

January 2025

Chongqing Key Laboratory of Reproductive Health and Digital Medicine, Department of Laboratory Medicine, Chongqing General Hospital, School of Medicine, Chongqing University, Chongqing 401147, China.

Diabetes exacerbates periodontitis by overexpressing reactive oxygen species (ROS), which leads to periodontal bone resorption. Consequently, it is imperative to relieve inflammation and promote alveolar bone regeneration comprehensively for the development of diabetic periodontal treatment strategies. Furthermore, an orderly treatment to avoid interference between these two processes can achieve the optimal therapeutic effect.

View Article and Find Full Text PDF

The results of a comprehensive investigation into the structure and properties of nanodiamond soot (NDS), obtained from the detonation of various explosive precursors (trinitrotoluene, a trinitrotoluene/hexogen mixture, and tetryl), are presented. The colloidal behavior of the NDS particles in different liquid media was studied. The results of the scanning electron microscopy, dynamic light scattering, zeta potential measurements, and laser diffraction analysis suggested a similarity in the morphology of the NDS particle aggregates and agglomerates.

View Article and Find Full Text PDF

This review explores biochar's potential as a sustainable and cost-effective solution for remediating organic pollutants, particularly polycyclic aromatic hydrocarbons (PAHs) and pesticides, in water. Biochar, a carbon-rich material produced from biomass pyrolysis, has demonstrated adsorption efficiencies exceeding 90% under optimal conditions, depending on the feedstock type, pyrolysis temperature, and functionalization. High surface area (up to 1500 m/g), porosity, and modifiable surface functional groups make biochar effective in adsorbing a wide range of contaminants, including toxic metals, organic pollutants, and nutrients.

View Article and Find Full Text PDF

Inhalable siRNA Targeting IL-11 Nanoparticles Significantly Inhibit Bleomycin-Induced Pulmonary Fibrosis.

ACS Nano

January 2025

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China.

For idiopathic pulmonary fibrosis (IPF), interleukin 11 (IL-11) is a pivotal cytokine that stimulates the transformation of fibroblasts into myofibroblasts, thus accelerating the progression of pulmonary fibrosis. Here, we develop an innovative inhalable small interfering RNA (siRNA) delivery system termed PEI-GBZA, which demonstrates impressive efficiency in loading siIL-11 targeting IL-11 (siIL-11) and substantially suppresses the differentiation of fibroblasts into myofibroblasts and epithelial-mesenchymal transition (EMT), reduces neutrophil and macrophage recruitment, and ultimately relieves the established fibrotic lesions in the IPF model. PEI-GBZA is prepared by modifying low-molecular-weight polyethylenimine (PEI) with 4-guanidinobenzoic acid (GBZA).

View Article and Find Full Text PDF

Probing the Design Rules for Optimizing Electron Spin Relaxation in Densely Packed Triplet Media for Quantum Applications.

ACS Mater Lett

January 2025

Department of Materials and London Centre for Nanotechnology, Imperial College London, South Kensington Campus, Exhibition Road, SW7 2AZ London, United Kingdom.

Quantum technologies using electron spins have the advantage of employing chemical qubit media with tunable properties. The principal objective of material engineers is to enhance photoexcited spin yields and quantum spin relaxation. In this study, we demonstrate a facile synthetic approach to control spin properties in charge-transfer cocrystals consisting of 1,2,4,5-tetracyanobenzene (TCNB) and acetylated anthracene.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!