Aims: To investigate associations between outdoor and screen time and changes in sleep patterns in children from two nationwide birth-cohorts in the SAPRIS project.
Methods: During the first French COVID-19 pandemic lockdown, volunteer parents of children enrolled in the ELFE and EPIPAGE2 birth-cohorts completed online questions about their child's outdoor time, screen time, and changes in sleep duration and quality compared with the pre-lockdown situation. In 5700 children (aged 8-9 years, 52% boys) with available data, we assessed associations between outdoor time, screen time, and sleep changes using multinomial logistic regression models adjusted for confounders.
Results: Children spent on average 3 h08 outdoors and 4 h34 using screens/day (3 h27 for leisure, 1 h07 for class-work). Sleep duration increased in 36% of children and decreased in 13.4%; sleep difficulties appeared/increased in 22.5% and decreased/disappeared/remained stable in 18.3%. After adjustment, increased screen time, especially for leisure, was associated with increased and decreased sleep duration (OR(95%CI) = 1.03(1.00-1.06) and OR = 1.06(1.02-1.10), respectively). No association was observed between outdoor time and sleep changes after adjustment.
Conclusions: Our study adds evidence for the association between high leisure-time screen time and shorter sleep time. It supports current screen guidelines for children, especially during leisure time and for those whose sleep duration is short.
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http://dx.doi.org/10.1111/cns.14128 | DOI Listing |
J Nat Med
January 2025
Chongqing Academy of Chinese Materia Medica, Chongqing University of Chinese Medicine, Chongqing, 402760, China.
Non-Hodgkin lymphomas (NHL), including diffuse large B-cell lymphoma (DLBCL), Burkitt lymphoma (BL), and follicular lymphoma (FL), predominantly arise from B cells undergoing germinal center (GC) reactions. The transcriptional repressor B-cell lymphoma 6 (BCL6) is indispensable for GC formation and contributes to lymphomagenesis via its BTB domain-mediated suppression of target genes. Dysregulation of BCL6 underpins the pathogenesis of GC-derived NHL.
View Article and Find Full Text PDFPediatr Res
January 2025
Division of Growth and Development, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Background: Equipping parents with play skills can foster child development. This study examined the effects of Power of Play Parent Intervention, a short, online, asynchronous, play skill enhancement program, on the frequency of total parent-child play, parents' attitude towards play, and children's screen time in Thailand.
Methods: From September to December 2023, 112 parents of children aged 12-36 months from social media platforms were block-randomized into two-arm, parallel groups (56 intervention and 56 waitlist control).
Abdom Radiol (NY)
January 2025
Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Purpose: Mesenteric artery embolism (MAE) is a relatively uncommon abdominal surgical emergency, but it can lead to catastrophic clinical outcomes if the diagnosis is delayed. This study aims to build a prediction model of clinical-radiomics nomogram for early diagnosis of MAE based on non-contrast computed tomography (CT) and biomarkers.
Method: In this retrospective study, a total of 364 patients confirmed as MAE (n = 131) or non-MAE (n = 233) who were randomly divided into a training cohort (70%) and a validation cohort (30%).
Cad Saude Publica
January 2025
Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Córdoba, Córdoba, Argentina.
This study aimed to identify latent (unobservable) dimensions representing specific physical activity-related behaviors and explore their potential effects on obesity burden and spatial distribution in Colombia. A cross-sectional study (n = 9,658) was conducted based on the Colombian National Survey of Nutritional Status. A generalized structural equations model was proposed, combining exposure and measurement models to define a disease model.
View Article and Find Full Text PDFComb Chem High Throughput Screen
January 2025
Andrology Department of Integrative Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Introduction: The traditional Chinese medicine formula, Bushen Daozhuo Granules (BSDZG), is used to treat chronic non-bacterial prostatitis (CNP) clinically. However, its mechanism of action is unclear. The aim of our study was to determine the effect of BSDZG on CNP and its underlying mechanisms.
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