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[Identification of meldonium in the urine of volunteers using high-performance liquid chromatography-tandem mass spectrometry after consumption of milk of cows treated with a preventive course of the veterinary drug Emidonol].
Vopr Pitan
November 2024
Federal Research Centre for Nutrition, Biotechnology and Food Safety, 109240, Moscow, Russian Federation.
Emidonol is a Russian antioxidant drug, widely used in veterinary medicine both for prophylactic purposes and under pathological conditions associated with oxygen deficiency. The product of its biotransformation in animals is meldonium, which is a metabolic modulator and has been included on the Prohibited List by the World Anti-Doping Agency (WADA) since 2016. In the presented research, volunteers once consumed samples of milk from cows that had undergone a 15-day course of the veterinary drug Emidonol® 10%, obtained from one of the farms in the Moscow region.
View Article and Find Full Text PDFMeldonium in milk and meat-An issue for professional athletes?
Drug Test Anal
July 2023
Analytical Chemistry Department, Kuban State University, Krasnodar, Russia.
Meldonium residues in milk: A possible scenario for inadvertent doping in sports?
Drug Test Anal
November 2021
Institute of Biochemistry and Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.
Lately, the veterinary drug Emidonol® has been discussed as a possible scenario for inadvertent doping in sports. Emidonol® is approved for use in livestock breeding, exhibiting antihypoxic and weak sedative effects. The veterinary drug rapidly dissociates into meldonium, a substance prohibited in sports, and is excreted largely in its unchanged form into urine.
View Article and Find Full Text PDFMeldonium determination in milk and meat through UHPLC-HRMS.
Heliyon
August 2020
Kuban State University, Analytical Chemistry Department, Krasnodar, 350040, Russia.
A simple and sensitive procedure for the quantification of meldonium in milk and meat by UHPLC-HRMS is presented. Some products were investigated to contain this substance due to using a veterinary drug called "Emidonol". According to the instruction for this drug, it can be used for injection (for cows) and as an additive in drinking water for chickens.
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