Plasma Cell Gingivitis and Its Mimics.

Oral Maxillofac Surg Clin North Am

Department of Oral Medicine & Pathology and Hospital Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 2 Thivon Street, 115 27, Goudi, Athens, Greece.

Published: May 2023

AI Article Synopsis

  • Plasma cell gingivitis (PCG) is an inflammatory condition of the gums marked by a high number of plasma cells in the tissue and does not improve with standard preventive treatments.
  • The condition is likely caused by hypersensitivity to certain substances like toothpastes, oral rinses, chewing gums, or spices.
  • Diagnosing PCG involves examining the patient's history and looking for conditions that mimic it, with patch tests sometimes used to pinpoint specific allergens.

Article Abstract

Plasma cell gingivitis (PCG) is an inflammatory condition that affects the gingival mucosa of the oral cavity. It is characterized by polyclonal dense plasma cell infiltrate in the connective tissue. Lesions do not respond to prophylactic treatment. Etiology is most likely hypersensitivity to certain antigens (eg, toothpastes, oral rinses, chewing gums, spices). Differential diagnosis of PCG includes reactive, granulomatous, and neoplastic lesions. The diagnostic workup is based on patient's history and the clinicopathologic correlation to rule out mimics of PCG. Dermatologic patch test may be indicated in chronic conditions to identify the allergen.

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Source
http://dx.doi.org/10.1016/j.coms.2022.10.003DOI Listing

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