Institutionalized and community-dwelling older adults have been greatly impacted by the coronavirus disease 2019 (COVID-19) pandemic with increased morbidity and mortality. The advent of vaccines and their widespread use in this population has brought about a dramatic turnaround in COVID-19 outcomes. The immunogenicity and effectiveness of the various vaccine options worldwide are discussed. Optimization of vaccine usage will still be important to maximize protection due to reduced initial immunity, development of variant strains, and fading of immunity over time. There are also lessons learned specific to older populations for future pandemics of novel pathogens.
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http://dx.doi.org/10.1016/j.idc.2022.11.002 | DOI Listing |
Alzheimers Dement
December 2024
Euro-Mediterranean University of Fez (UEMF), Fez, Fez, Morocco.
Background: The spread of fake news may lead to a disparate wave of digital health-seeking behavior, cyberchondria, anxiety, indecision, and other psychosocial dysfunctions, including collapse in social capital and stigmatization. In this study, we utilized a bibliometric analysis to discern the primary trends associated with health communication and health-seeking behavior regarding dementia-related contents in countries within the Middle East and North African (MENA) region.
Method: A literature review was conducted in November 2023.
Clin Nurs Res
January 2025
Institute of Human Genetics, Faculty of Medicine, University of Belgrade, Serbia.
The hypoxia-inducible factor-1 alpha (HIF-1 alpha) is a major regulator of adaptive response to hypoxia, common in patients with severe coronavirus disease 2019 (COVID-19). In addition, HIF-1 alpha regulates the expression of the most important proteins necessary for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of cells. The study included 129 hospitalized COVID-19 patients.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Background: Cardiometabolic diseases and mental health disorders, which are high-risk factors for dementia and cognitive decline, are associated with higher mortality and morbidity with age. Interventions before age 60 may lessen the burden of cognitive and physical function in later life. Telehealth offers early intervention and solutions for their complex demands in continuous behavior monitoring and medication refilling.
View Article and Find Full Text PDFPrim Health Care Res Dev
January 2025
Shenzhen Elderly Healthcare College, Shenzhen Polytechnic University, Shenzhen, China.
Aim: This research aimed to comprehensively explore the impact of diverse challenges encountered by older adults on the development of post-traumatic stress disorder (PTSD). It delved into how these effects vary depending on individuals' levels of trust in authority and medical professionals, providing a nuanced understanding of the interplay between external challenges, personal trust, and mental health outcomes in the older population.
Background: The COVID-19 pandemic has imposed significant hardships, particularly on the ageing population, with potential psychological repercussions such as PTSD.
Int J Med Sci
January 2025
Department of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, Kingdom of Saudi Arabia.
The outbreak of COVID-19 has opened up new avenues for exploring the importance of vitamin D in immunity, in addition to its role in calcium absorption. Recently, vitamin D supplementation has been found to enhance T regulatory lymphocytes, which are reduced in individuals with COVID-19. Increased risk of pneumonia and increases in inflammatory cytokines have been reported to be major threats associated with vitamin-D deficiency.
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