Post-synthesis introduction of dual functional groups in metal-organic framework for enhanced adsorption of moxifloxacin antibiotic.

Highly effective removal of antibiotics from aqueous solution is of importance while still faces challenge. Herein, we report a novel metal-organic framework (MOF) adsorbent, MOF-808-SIPA (SIPA, 5-sulfoisophthalic acid), constructed via post-synthesis exchange strategy. On the basis, dual active groups including sulfonic acid and carboxyl groups are successfully introduced. The novel MOF-808-SIPA exhibits a high adsorption capacity of 287.1 mg g for moxifloxacin hydrochloride (MOX·HCl), superior to that (174.6 mg g) of the pristine MOF-808-AA (AA, acetic acid). Besides, MOF-808-SIPA shows rapid adsorption equilibrium of ∼ 30 min, strong anti-interference ability from pH and inorganic ions, and feasible regeneration. The superiority renders MOF-808-SIPA a potential adsorbent for MOX removal. Density function theory (DFT) calculation and experiment confirm that H-bond interaction contributes largely to the excellent adsorption in MOF-808-SIPA. Our work provides a guideline for designing high-efficiency MOF-based adsorbent.