AI Article Synopsis
- Prevention is crucial in public health, but innovative drugs are essential for controlling and eliminating neglected diseases.
- Advances in drug discovery technologies and scientific knowledge are transforming research and development in this area.
- The text specifically highlights the progress in treating parasitic infections like malaria, while addressing challenges and priorities for creating new antiparasitic medications.
Article Abstract
While prevention is a bedrock of public health, innovative therapeutics are needed to complement the armamentarium of interventions required to achieve disease control and elimination targets for neglected diseases. Extraordinary advances in drug discovery technologies have occurred over the past decades, along with accumulation of scientific knowledge and experience in pharmacological and clinical sciences that are transforming many aspects of drug R&D across disciplines. We reflect on how these advances have propelled drug discovery for parasitic infections, focusing on malaria, kinetoplastid diseases, and cryptosporidiosis. We also discuss challenges and research priorities to accelerate discovery and development of urgently needed novel antiparasitic drugs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.pt.2023.01.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!