AI Article Synopsis
- Researchers investigated if the size of skeletal muscles before immobilization influences muscle loss after 14 days of immobilizing one leg.
- Results showed that overall, initial muscle size didn't affect the amount of muscle atrophy experienced.
- However, some sex differences were noted, with women showing a link between their pre-immobilization muscle size and changes in muscle size during immobilization, warranting further study.
Article Abstract
We aimed to determine whether there was a relationship between pre-immobilization skeletal muscle size and the magnitude of muscle atrophy following 14 days of unilateral lower limb immobilization. Our findings ( = 30) show that pre-immobilization leg fat-free mass and quadriceps cross-sectional area (CSA) were unrelated to the magnitude of muscle atrophy. However, sex-based differences may be present, but confirmatory work is required. In women, pre-immobilization leg fat-free mass and CSA were associated with changes in quadriceps CSA after immobilization ( = 9, = 0.54-0.68; < 0.05). The extent of muscle atrophy is not affected by initial muscle mass, but there is potential for sex-based differences.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1139/apnm-2022-0458 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!