AI Article Synopsis
- Sarcoma is a type of tumor that can occur anywhere in the body, with synovial sarcoma being a rare and aggressive soft tissue tumor that typically appears in the joints.
- Primary synovial sarcoma in the lung and mediastinum is very uncommon and usually malignant, with limited documented cases.
- Diagnosis involves histopathological and cytogenetic exams, and treatment often combines surgery, chemotherapy, and radiotherapy, which can improve five-year survival rates if adjuvant therapies are utilized.
Article Abstract
Sarcoma is defined as a tumor located in the thoracic cavity. However, sarcoma can occur on every side of the body. Synovial sarcoma is a rare soft tissue tumor originating from pluripotent with a high malignancy rate. The most common predilection of synovial sarcoma is in the joints. Primary synovial sarcoma of the lung and mediastinum are rare tumors and generally malignant. There are only a few cases have been reported. Definite diagnosis is made by histopathological, immunohistochemistry, and cytogenetic examination. The management strategy for synovial sarcoma requires multimodality treatment with surgery, chemotherapy, and radiotherapy. However, effective and relatively non-toxic therapy for primary synovial sarcoma is still developed. The five years life expectancy is higher if the patient received adjuvant radiotherapy and/or chemotherapy after surgery.
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| http://dx.doi.org/10.1515/jbcpp-2022-0286 | DOI Listing |
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