Objective: To determine the impact of high-energy nutritional supplements on appetite, appetite regulators, energy intake and macronutrients level among underweight primigravidae.
Methods: The single-blind randomised controlled trial was conducted from April 26, 2018, to August 10, 2019, in tertiary care hospitals of Khyber Pakhtunkhwa province of Pakistan, after approval from the ethics review committee of Khyber Medical University, Peshawar, and comprised underweight primigravidae who were randomly allocated to high energy nutritional supplement group A and placebo group B. Appetite questionnaires were filled and blood samples were obtained in fasting state, at 30, 60, 120, 210 and 270 minutes to measure blood glucose, insulin, peptide YY and cholecystokinin. Breakfast and lunch were served at 30 minutes and 210 minutes after supplementation, respectively. Data was analysed using SPSS 20.
Results: Of the 36 subjects, 19(52.8%) were in group A and 17(47.2%) were in group B. The overall mean age was 18.66 ± 2.5 years. Energy intake in group A was significantly higher than group B (p<0.001), and so were mean protein and fats (p<0.001). The subjective appetite perceptions for 'hunger' and 'desire to eat' were significantly lower (p<0.001) before lunch in group A. Plasma concentrations of appetite hormones corresponded to the appetite perceptions and were significantly higher in group A after breakfast and lunch for peptide YY, cholecystokinin and insulin compared to group B (p<0.001).
Conclusions: High-energy nutritional supplement was found to have short-term suppressive effect on energy intake and appetite.
Trial Registration: ClinicalTrials.gov Identifier: ISRCTN 10088578. Registered on 27 March 2018. https://www.isrctn.com/ ISRCTN10088578.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.47391/JPMA.5171 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Insight into the Role and Evidence of Oxygen Vacancies in Porous Single-Crystalline Oxide to Enhance Catalytic Activity and Durability.
Research (Wash D C)
September 2023
Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Introducing and stabilizing oxygen vacancies in oxide catalysts is considered to be a promising strategy for improving catalytic activity and durability. Herein, we quantitatively create oxygen vacancies in the lattice of porous single-crystalline β-GaO monoliths by reduction treatments and stabilize them through the long-range ordering of crystal lattice to enhance catalytic activity and durability. The combination analysis of time-of-flight neutron powder diffraction and extended x-ray absorption fine structure discloses that the preferential generation of oxygen vacancy tends to occur at the site of tetrahedral coordination oxygen ions (O sites), which contributes to the formation of unsaturated Ga-O coordination in the monoclinic phase.
View Article and Find Full Text PDFA review of recent advancements in the impact response of fiber metal laminates.
Heliyon
January 2025
Natural Composites Research Group Lab, Department of Materials and Production Engineering, The Sirindhorn International Thai-German School of Engineering (TGGS), King Mongkut's University of Technology North Bangkok (KMUTNB), Bangkok, 10800, Thailand.
Fiber metal laminates (FMLs) have garnered significant attention due to their exceptional impact resistance, making them attractive for various structural applications. This review presents recent advancements in understanding the impact behavior of FMLs under low- and high-velocity impact scenarios. Low-velocity impacts, commonly encountered during manufacturing, handling, and tool drops, are discussed, with a focus on damage mechanisms, energy absorption capabilities, and influential factors such as impactor geometry and boundary conditions.
View Article and Find Full Text PDFThis study used coal combustion products (CCP) with different calcium contents to replace partial aluminate cement (AC) in equal amounts, and studied the effect of calcium contents on the setting time and early compressive strength of AC. The setting time and early compressive strength were further regulated by adding retarder. The results showed that the higher the calcium content of CCP (CCP2 contains higher calcium content), the shorter the setting time and the higher the 2 h compressive strength after replacing part of cement.
View Article and Find Full Text PDFPracticing Emotional Self-awareness to Build Surgeon Resilience.
Plast Reconstr Surg Glob Open
January 2025
From the Division of Plastic Surgery, Department of Surgery, Barnes Jewish Hospital, Washington University, St. Louis, MO.
As surgeons, we work in a high-stress, high-stakes environment to take care of our patients. In this setting, it is not uncommon for us to experience microaggressions-subtle or indirect actions or statements that communicate a demeaning or exclusionary message, often unintentionally. Microaggressions can bring us down, taking away from the fulfillment that attracted many of us to this profession.
View Article and Find Full Text PDFInfluence of Acquisition Parameters on Silver Sulfide Nanoparticle Contrast in Photon-Counting Digital Mammography: A Phantom Study.
ACS Appl Nano Mater
March 2024
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Photon-counting mammography is an emerging modality that allows for spectral imaging and provides a differentiation of material compositions. The development of photon-counting mammography-specific contrast agents has yet to be explored. In this study, the contrast, sensitivity, and organ dose between silver sulfide nanoparticles (AgS-NPs) and a clinically approved iodinated agent (iopamidol) were investigated using a contrast-embedded gradient ramp phantom and a prototype scanner.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!