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The nervous system predicts and executes complex motion of body segments actuated by the coordinated action of muscles. When a stroke or other traumatic injury disrupts neural processing, the impeded behavior has not only kinematic but also kinetic attributes that require interpretation. Biomechanical models could allow medical specialists to observe these dynamic variables and instantaneously diagnose mobility issues that may otherwise remain unnoticed. However, the real-time and subject-specific dynamic computations necessitate the optimization these simulations. In this study, we explored the effects of intrinsic viscoelasticity, choice of numerical integration method, and decrease in sampling frequency on the accuracy and stability of the simulation. The bipedal model with 17 rotational degrees of freedom (DOF)-describing hip, knee, ankle, and standing foot contact-was instrumented with viscoelastic elements with a resting length in the middle of the DOF range of motion. The accumulation of numerical errors was evaluated in dynamic simulations using swing-phase experimental kinematics. The relationship between viscoelasticity, sampling rates, and the integrator type was evaluated. The optimal selection of these three factors resulted in an accurate reconstruction of joint kinematics (err < 1%) and kinetics (err < 5%) with increased simulation time steps. Notably, joint viscoelasticity reduced the integration errors of and had minimal to no additional benefit for . Gained insights have the potential to improve diagnostic tools and accurize real-time feedback simulations used in the functional recovery of neuromuscular diseases and intuitive control of modern prosthetic solutions.
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http://dx.doi.org/10.1101/2023.02.09.527805 | DOI Listing |
Compr Physiol
December 2024
School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
The evolution of mechanisms for terrestrial locomotion has resulted in multi-segmented limbs that allow navigation on irregular terrains, changing of direction, manipulation of external objects, and control over the mechanical properties of limbs important for interaction with the environment, with corresponding changes in neural pathways in the spinal cord. This article is focused on the organization of these pathways, their interactions with the musculoskeletal system, and the integration of these neuromechanical circuits with supraspinal mechanisms to control limb impedance. It is argued that neural pathways from muscle spindles and Golgi tendon organs form a distributive impedance controller in the spinal cord that controls limb impedance and coordination during responses to external disturbances.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
Key Laboratory of Advanced Materials for Facility Agriculture, Ministry of Agriculture, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Given the limitations of single-function electromagnetic wave-absorbing materials (EWAMs) in meeting the evolving demands of complex usage scenarios, there is a growing need for structure-function integrated composites that offer a combination of microwave absorption, human monitoring, and thermal insulation. This study successfully synthesized two-dimensional (2D) TiCT MXene via selective etching of Al from the TiAlC MAX phase. By introducing MXene into a composite of hydroxylated CoFeO nanoparticles (-CFO NPs) and bacterial nanocellulose (BNC) to modulate the electromagnetic performance of the EWAMs.
View Article and Find Full Text PDFJ Sport Health Sci
December 2024
Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo 0806, Norway.
Background: High adiposity and low physical activity are associated with cancer risk. Whether different amounts and intensities of physical activity can mitigate this association is unclear. We aimed to examine the independent and combined associations of adiposity and device-measured physical activity levels of different intensities with cancer incidence and mortality.
View Article and Find Full Text PDFInorg Chem
December 2024
School of Marine Science and Engineering, Hainan University, Haikou 570228, China.
Cureus
November 2024
Department of Joint Research in Advanced Medicine for Electromagnetic Engineering, Shimane University, Izumo, JPN.
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