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Effect of immune checkpoint inhibitor time-of-day infusion on survival in advanced biliary tract cancer: a propensity score-matched analysis.
Front Immunol
January 2025
Department of Medical Oncology, Cancer Center and Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: Circadian rhythms in the immune system and anti-tumor responses are underexplored in cancer immunotherapy. Despite the success of immune checkpoint inhibitors (ICIs) in treating advanced biliary tract cancers (BTCs), not all patients benefit. This study examined whether the timing of ICI administration affects outcomes in advanced BTC patients.
View Article and Find Full Text PDFEnteral Feeding in Patients With Open Abdomen and Negative Pressure Therapy: A Propensity Score Analysis.
J Abdom Wall Surg
December 2024
Anesthesiology and Critical Care Department, Pellegrin University Hospital, Bordeaux, France.
Introduction: In critically ill surgical patients treated with open abdomen and negative pressure therapy (OA/NPT), the association between nutritional support and clinical outcome is still controversial. The main objective of this study was to assess the effect of enteral nutritional support during the acute phase (i.e.
View Article and Find Full Text PDFCase report: Improving quality of life through hyaluronic acid-based fillers after orbital cancer treatment.
Front Oncol
December 2024
Department of Pediatrics, Sapienza University, Rome, Italy.
Background: Myoepithelial carcinoma is a very rare yet aggressive tumor in children. Surgical intervention and local radiotherapy often lead to post-therapy complications, affecting both the aesthetic and functional quality of life in survivors. Hyaluronic acid (HA) dermal fillers offer a minimally invasive option to improve the appearance and quality of life for these patients once they are declared tumor-free.
View Article and Find Full Text PDFOrthodontic treatment of deep bite in mixed dentition and/or early permanent dentition: What about stability? - A systematic review.
Int Orthod
December 2024
Department of Dentofacial Orthopedics, Faculty of Dental Medicine, Mohammed V University in Rabat, Rabat, Morocco.
Introduction: Deepbite is a vertical malocclusion found alone or in association with other types of sagittal and transverse disorders. With a high relapse tendency, deepbite is considered one of the most challenging malocclusions to treat. It is commonly found in mixed dentition with increased prevalence of 21.
View Article and Find Full Text PDFComprehensive Analysis of Thrombotic Microangiopathy Following Renal Transplantation.
Int J Nephrol
December 2024
Department of Cell and Developmental Biology, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.
Thrombotic microangiopathy is a severe complication of renal transplantation. Little is known about risk factors, incidence of autoantibodies against complement components, and prognosis. Clinical and laboratory data were retrospectively collected for 13 patients diagnosed with post-transplant thrombotic microangiopathy (PT-TMA) in 2011-2018.
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