AI Article Synopsis

  • Polycaprolactone has shown promise as a biomaterial for bone regeneration, particularly in the context of dental implants.
  • This report details the first clinical application of a 3D printed polycaprolactone mesh used for alveolar ridge augmentation in two patients who required significant bone enhancement.
  • After 2 years, patients experienced bone gains of about 6 mm vertically and 8 mm horizontally, although there was some reduction in ridge dimensions post-surgery, indicating potential effectiveness but also the need for further studies.

Article Abstract

Polycaprolactone has exhibited expediency as a biomaterial for bone regenerative procedures preclinically. The present report of the two clinical cases in the posterior maxilla is the first to describe clinical application of a customized 3D printed polycaprolactone mesh for alveolar ridge augmentation. Two patients needing extensive ridge augmentation procedures for dental implant therapy were selected. Polycaprolactone meshes were virtually designed, 3D printed and applied in combination with a xenogeneic bone substitute. Cone-beam computed tomography was taken pre-operatively, immediately after the surgery, and 1.5 to 2 years after the delivery of implant prostheses. The serial cone-beam computed tomography images were superimposed to measure the augmented height and width at 1 mm increments from the implant platform to 3 mm apically. After 2 years, the mean [maximum, minimum] bone gain was 6.05 [8.64, 2.85] mm vertically and 7.77 [10.03, 6.18] mm horizontally at 1 mm below the implant platform. From immediately postoperative to 2 years, there was 14 % reduction of augmented ridged height and 24 % reduction of augmented width at 1 mm below the platform. All implants placed in augmented sites were successfully maintained until 2 years. The customized Polycaprolactone mesh might be a viable material for ridge augmentation in the atrophic posterior maxilla. This needs to be confirmed through randomized controlled clinical trials in future studies.

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Source
http://dx.doi.org/10.1563/aaid-joi-D-22-00007DOI Listing

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