AI Article Synopsis
- - This study examined how different types of social adversity (like neighborhood conditions and life stress) impact genetic and environmental influences on behaviors like aggression and delinquency among twins aged 10-11.
- - Findings revealed that as neighborhood adversity increases, the influence of shared environmental factors on these behaviors grows, while genetic influences decrease.
- - The results indicate that at higher levels of adversity, environmental factors become more significant, suggesting that a lack of resources can heighten genetic risks for negative behaviors, thus highlighting the need for better measurement of social adversity in research.
Article Abstract
This study tested whether multiple domains of social adversity, including neighborhood opportunity/deprivation and life stress, moderate genetic (A), common environmental (C), and unique environmental (E) influences on externalizing behaviors in 760 same-sex twin pairs (332 monozygotic; 428 dizygotic) ages 10-11 from the ABCD Study. Proportion of C influences on externalizing behavior increased at higher neighborhood adversity (lower overall opportunity). A decreased and C and E increased at lower levels of educational opportunity. A increased at lower health-environment and social-economic opportunity levels. For life stress, A decreased and E increased with number of experienced events. Results for educational opportunity and stressful life experiences suggest a bioecological gene-environment interaction pattern such that environmental influences predominate at higher levels of adversity, whereas limited access to healthcare, housing, and employment stability may potentiate genetic liability for externalizing behavior via a diathesis-stress mechanism. More detailed operationalization of social adversity in gene-environment interaction studies is needed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933005 | PMC |
| http://dx.doi.org/10.1007/s10519-023-10136-z | DOI Listing |
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