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Nail Lichen Striatus and Its Differential Diagnoses.
Skin Appendage Disord
December 2024
Private Dermatology Clinic, Antalya, Turkey.
Background: Lichen striatus (LS) is a benign, mostly self-limiting dermatological condition, primarily affecting the skin, and sometimes the nails. It is characterised by the sudden onset of a band-like rash, typically following Blaschko lines. The exact cause of LS is not well established, but it is believed to be an abnormal immune response to the altered keratinocyte clone after a triggering event.
View Article and Find Full Text PDF[Blaschko-linear atrophic lichen planus pigmentosus].
Dermatologie (Heidelb)
November 2024
Department for Dermatology, Venereology und Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Luisenstr. 2, 10117, Berlin, Deutschland.
From Clinical Observation to Genetic Confirmation: Somatic Mosaic Mutations in RHOA on Ectodermal Dysplasia With Multi-System Involvement.
Am J Med Genet A
November 2024
Pediatric Genetics, Ege University, Izmir, Turkey.
Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies (EDFAOB) is a rare neuroectodermal syndrome caused by somatic mosaic mutations in the RHOA gene. It presents with linear skin hypopigmentation, facial and limb asymmetry, dental and acral anomalies, and leukoencephalopathy, generally preserving intellectual and neurological functions. We report two cases of EDFAOB.
View Article and Find Full Text PDFLinear Psoriasis in a Pediatric Patient Successfully Treated With Ixekizumab.
Pediatr Dermatol
November 2024
Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Linear psoriasis is a rare clinical presentation of psoriasis characterized by erythematous scaly plaques distributed along Blaschko's lines. We describe an 8-year-old male with a linear Blaschkoid plaque in which biopsy findings and clinical history were consistent with linear psoriasis. The lesion showed only mild improvement with topical steroid therapy but exhibited significant clearance with the biologic agent ixekizumab, an IL-17A inhibitor.
View Article and Find Full Text PDFLinear atrophoderma of Moulin (LAM) is an uncommon dermatological disease characterised by linear, depressed plaques typically following Blaschko's lines. LAM generally occurs in adolescence or early adulthood and is more commonly observed in females. The aetiology of LAM is still unclear.
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