Purpose: This report describes the case of unilateral central retinal artery occlusion (CRAO) as a patient's presenting clinical sign of systemic lupus erythematosus (SLE).
Observations: Though the patient knew of her SLE diagnosis through incidental abnormal lab work, she never pursued treatment because she never exhibited signs of the disease. Despite her asymptomatic course, she presented with a sudden and severe thrombotic event that left her with no light perception in her affected eye. Laboratory work-up was consistent with SLE and anti-phospholipid syndrome (APS).
Conclusions And Importance: This case draws attention to the possibility of CRAO as a presenting sign of SLE, rather than a sequela of active disease. Awareness of this risk may play a factor in future discussions between patients and their rheumatologists when considering initiation of treatment at the time of diagnosis.
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http://dx.doi.org/10.1016/j.ajoc.2023.101810 | DOI Listing |
Front Med (Lausanne)
December 2024
Department of Nephrology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
This report primarily describes a rare case of an elderly male patient who initially presented with central retinal artery occlusion (CRAO) in the left eye and was ultimately diagnosed with anti-neutrophil cytoplasmic antibody (ANCA) -associated vasculitis involving the eyes, gastrointestinal tract, and kidneys. However, due to irregular treatment, both eyes developed progressive ocular manifestations later. This article emphasizes the importance of actively screening for and treating underlying conditions in cases of CRAO.
View Article and Find Full Text PDFWorld J Clin Oncol
December 2024
Department of Ophthalmology, The Sixth Affiliated Hospital of Jinan University, Dongguan 523000, Guangdong Province, China.
Background: Both rhabdomyosarcoma (RMS) and central retinal artery occlusion (CRAO) are rare medical diseases, and their simultaneous occurrence in the same patient is extraordinarily uncommon. This study presents a comprehensive overview of the clinical manifestations, diagnostic imaging results, and therapeutic interventions of a patient with both conditions.
Case Summary: In this report, we present a 30-year-old male who presented with significant protrusion, pain and vision loss and was diagnosed with RMS in the orbit and sinus with CRAO.
Pan Afr Med J
December 2024
Department of Ophthalmology, Faculty of Medicine Airlangga University, Dr. Soetomo General Academic Hospital Surabaya, Surabaya, Indonesia.
Central Retinal Artery Occlusion (CRAO) is a serious ophthalmic emergency characterized by sudden, painless vision loss in one eye. This condition leads to rapid and significant visual impairment if not treated promptly. This case illustrates an adult man with hypertension presented with unilateral, painless, sudden vision loss occurring 13 hours before admission.
View Article and Find Full Text PDFCureus
November 2024
Department of Medicine, Dr. Baba Saheb Ambedkar Medical College and Hospital, New Delhi, IND.
This report describes a rare presentation of atypical hemolytic uremic syndrome with multi-system involvement, including unilateral blindness and stroke. Only a few cases of atypical hemolytic uremic syndrome with unilateral blindness as a presentation have been reported and all have been attributed to central retinal artery obstruction (CRAO). This is the first described case to our knowledge of atypical hemolytic uremic syndrome presenting with unilateral blindness, which was caused by grade four hypertensive retinopathy.
View Article and Find Full Text PDFOphthalmol Sci
October 2024
Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Objective: To demonstrate the capability of a deep learning model to detect central retinal artery occlusion (CRAO), a retinal pathology with significant clinical urgency, using OCT data.
Design: Retrospective, external validation study analyzing OCT and clinical baseline data of 2 institutions via deep learning classification analysis.
Subjects: Patients presenting to the University Medical Center Tübingen and the University Medical Center Hamburg-Eppendorf in Germany.
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