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Malignant thyroid neoplasm with ectopic Cushing's syndrome.
BMJ Case Rep
December 2024
Endocrinology, PGIMER, Chandigarh, India.
An adult man in his 30s with newly diagnosed diabetes mellitus and hypertension presented with a 33 lb weight gain, generalised swelling and classic Cushingoid features, including proximal muscle weakness, easy bruisability, wide violaceous striae and a painless, progressively enlarging right-sided neck swelling over the past month. Physical examination revealed a 4×4 cm thyroid mass, facial plethora and dorsocervical fat pads. Laboratory investigations confirmed hypercortisolism with elevated cortisol and Adrenocorticotropic Hormone(ACTH), with non-suppression on dexamethasone suppression tests.
View Article and Find Full Text PDFEpidermodysplasia Verruciformis (Lewandowsky and Lutz's Dysplasia).
Skinmed
September 2024
Pathology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
A woman in her twenties, with a non-consanguineous marriage, presented to the dermatology clinic with asymptomatic lesions on her face, neck, trunk, and extremities for the past 12 years. The general physical and systemic examination was unremarkable. Cutaneous examination revealed multiple hypopigmented to a few hyperpigmented, slightly scaly tinea versicolor-like macules distributed predominantly on the neck, upper portion of the back, and distal parts of the extremities (Figures 1-5).
View Article and Find Full Text PDFUlcerative erythematous papules and plaques on the face and lower legs of a man living with HIV: a clinicopathological challenge.
Int J Dermatol
November 2024
Department of Dermatology, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA.
Article Synopsis
- * His facial lesions appeared as violaceous plaques, while his lower legs displayed ulcerative lesions with necrosis and purple borders, resembling pyoderma gangrenosum and cutaneous lymphoma.
- * A biopsy and rapid plasma reagin test confirmed the diagnosis of lues maligna, leading to successful treatment with penicillin G benzathine.
Case report: "Fur stole and turtleneck" and "halter-back" signs: an expanded wardrobe for dermatomyositis.
Front Immunol
June 2024
Department of Medicine, The University of the West Indies, Mona, Kingston, Jamaica.
A diagnosis of dermatomyositis requires recognition of distinct patterns of skin disease in combination with, and sometimes without, muscle weakness. Often, a striking contrast between involved and uninvolved areas is observed. Familiar patterns include eyelid and midfacial eruptions, Gottron papules/sign, and upper back (shawl sign), central chest (V/open collar sign), and lateral thigh (holster sign) involvement.
View Article and Find Full Text PDFAsymptomatic Violaceous Plaques on the Face and Back.
Cutis
January 2024
Medical University of South Carolina, Charleston. Dr. DeVore is from the College of Medicine, and Dr. Elston is from the Department of Dermatology and Dermatologic Surgery.
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