Propolis is a resinous substance containing aromatic acids, esters, volatile compounds, hydrocarbons, steroids, enzymes, flavonoids, vitamins and minerals. In this direction it has nutrient, antibacterial and antioxidant properties due to its complex structure and content. In this study it was aimed to prepare a propolis ointment with a base of occlusive and emollient properties for nourishing and healing of skin damaged by environmental effects. Six formulations were prepared by using vaseline, lanolin, glycerine and different types of crude propolis. According to physical examinations only the ointment formulations prepared with ethanolic propolis extracts at two different concentrations were found as successful. Successful formulation including 1:5 propolis: Ethanol extract was evaluated by physical controls, mechanic tests, antimicrobial tests and stability evaluation. Results showed that prepared propolis ointment has a creamy yellow colour with an acceptable odour, homogeny and a good spreadability texture and has a good stability at 40C and 25C and for 2 and 3 months respectively. And it presented mild antibacterial effects on E. coli and S. aureus strains, which was acceptable for a frequent use for cosmetic purposes. As a conclusion prepared propolis ointment can be a good candidate for a cosmetic ointment for skin nutrition and healing purposes.
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Biomed Phys Eng Express
December 2024
Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences (UVAS), Lahore, Pakistan.
Developing an efficient and cost-effective wound-healing substance to treat wounds and regenerate skin is desperately needed in the current world. The present study evaluatedwound healing andantioxidant, antibacterial, anti-inflammatory activities of propolis mediated silver nanoparticles. Extract of Bee propolis from northeast Punjab, Pakistan, has been prepared via maceration and subjected to chemical identification.
View Article and Find Full Text PDFAntibiotics (Basel)
November 2024
Aix Marseille Université, INSERM, SSA, MCT, 13385 Marseille, France.
Background/objectives: Acne is the most prevalent dermatological condition among humans, affecting approximately 80% of adolescents during puberty. To date, numerous compounds have been used for acne treatment, including erythromycin ointments and antiseptics, with varying degrees of success. The emergence of erythromycin-resistant strains has spurred the search for new antimicrobial agents, particularly from natural sources.
View Article and Find Full Text PDFInt J Mol Sci
October 2024
Agricultural Science and Technology Research Institute, Andong National University, Andong 36729, Republic of Korea.
Propolis, such as is used as bio-cosmetics and in functional materials, is increasing because of its antioxidant medicinal benefits. However, its pharmacological and chemical composition is highly variable, relative to its geography and botanical origins. Comparative studies on three propolis samples collected from different regions in Korea have been essential for linking its provenance, chemical composition, and biological activity, thereby ensuring the efficient utilization of its beneficial properties.
View Article and Find Full Text PDFAdv Biomed Res
August 2024
Department of Parasitology and Mycology, Skin Diseases and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Cutaneous leishmaniasis (CL) infection is caused by the parasite and affects 1.5 to 2 million people worldwide each year. Although research into vaccines and antiparasitic drugs has been somewhat successful, their adverse effects include high toxicity, prolonged regeneration, and scarring.
View Article and Find Full Text PDFRev Bras Enferm
September 2024
Universidade Federal de São Paulo. São Paulo, São Paulo, Brazil.
Objective: to assess the effectiveness of 5% Brazilian green propolis (ointment) in individuals with chronic ulcers.
Methods: a randomized clinical trial, developed with 40 patients randomized equally to control group (treated with essential fatty acid) and experimental group (treated with 5% green propolis) for 30 days. The outcomes of interest were sociodemographic, clinical and laboratory characteristics, lesion characteristics, such as type of tissue in the bed, presence of exudate, edge characteristics, microbial content and pain.
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