Maternal hyperoxygenation (MHO) consists of giving pregnant women (60% to 100%) oxygen through a facemask and using ultrasound assess or monitor the influence on fetal cardiovascular circulation. This review discusses the findings and the utility of acute and chronic MHO in various fetal diseases.
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Establishing dosing parameters for the use of maternal hyperoxygenation to affect fetal cardiovascular physiology.
J Am Soc Echocardiogr
January 2025
Division of Pediatric Cardiology, Department of Pediatrics, Stanford School of Medicine, Stanford, CA.
Acute maternal hyperoxygenation to predict hypoxia and need for emergency intervention in fetuses with transposition of the great arteries: a pilot study.
J Am Soc Echocardiogr
January 2025
Department of Congenital Heart Disease, Evelina London Children's Hospital, Guy's & St Thomas' NHS Trust, Westminster Bridge Road, London SE1 7EH, UK; School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Background: Newborns with transposition of the great arteries (TGA) are at risk of severe hypoxia from inadequate atrial mixing, closure of the arterial duct and/or pulmonary hypertension (PPHN). Acute maternal hyperoxygenation (AMH) might assist in identifying at-risk fetuses. We report pulmonary vasoreactivity to AMH in TGA fetuses and its relationship to early postnatal hypoxia and requirement for emergency balloon atrial septostomy (e-BAS).
View Article and Find Full Text PDFAcute maternal hyperoxygenation protocol: consensus opinion from the Fetal Heart Society.
Ultrasound Obstet Gynecol
November 2024
Division of Pediatric Cardiology, Ann and Robert H Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Role of maternal hyperoxygenation in predicting need for postnatal balloon atrial septostomy in fetal d-transposition of the great arteries.
Ultrasound Obstet Gynecol
November 2024
Fetal Heart Program, Division of Pediatric Cardiology, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
Objective: Predicting whether postnatal balloon atrial septostomy (BAS) will be necessary for fetuses with dextro-transposition of the great arteries (d-TGA) remains challenging. We sought to determine whether fetal echocardiographic measurements obtained during maternal hyperoxygenation (MH) can improve our ability to predict the need for postnatal BAS.
Methods: This was a retrospective, single-institution review of d-TGA fetuses whose mothers had undergone MH at 33-38 weeks' gestation at the Children's Hospital of Philadelphia, between 1 January 2017 and 30 March 2020.
Advances in Fetal Cardiac Imaging and Intervention.
CJC Pediatr Congenit Heart Dis
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The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
The field of fetal cardiology has evolved significantly in recent years. This review focuses on specific advances in fetal cardiac imaging and intervention that are increasingly used in clinical practice. On the imaging frontier, updated screening guidelines and artificial intelligence hold promise for improving prenatal detection of congenital heart disease.
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