Effects of diet containing astaxanthin on visual function in healthy individuals: a randomized, double-blind, placebo-controlled, parallel study.

J Clin Biochem Nutr

Miura Clinic, Medical Corporation Kanonkai, 9th Floor, Higashi-Tenma-Building, 1-7-17 Higashi-Tenma, Kita-ku, Osaka 530-0044, Japan.

Published: January 2023

AI Article Synopsis

Article Abstract

Visual display terminal work has increased rapidly in recent years. Loss of visual acuity is an unfortunate associated effect. Here, we performed a randomized, placebo-controlled study in 60 healthy adults. Participants received a diet containing astaxanthin (9 mg/day) or placebo for 6 weeks. Visual acuity, functional visual acuity, and pupil constriction rate were measured before and after visual display terminal work. In participants aged ≥40 years, corrected visual acuity of the dominant eye after visual display terminal work at 6 weeks after intake demonstrated a higher protective effect of astaxanthin in the astaxanthin group vs the control group (<0.05). In participants aged <40 years, no significant difference was seen between the astaxanthin and control groups. Moreover, no significant difference was found in functional visual acuity and pupil constriction rate between the astaxanthin and control groups. These results suggest astaxanthin reduces oxidative stress caused by visual display terminal work. Age-related reduction in ciliary muscle strength is likely the main detractor of visual acuity. Correspondingly, astaxanthin reduced visual display terminal work-induced visual stress in the middle-aged and elderly. This study was registered in the UMIN-CTR database (UMIN000043089).

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899915PMC
http://dx.doi.org/10.3164/jcbn.22-65DOI Listing

Publication Analysis

Top Keywords

visual acuity
16
visual display
12
display terminal
12
terminal work
12
diet astaxanthin
8
visual
8
effects diet
4
astaxanthin
4
astaxanthin visual
4
visual function
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!