Brain-computer interfaces (BCIs), such as the P300 speller, can provide a means of communication for individuals with severe neuromuscular limitations. BCIs interpret electroencephalography (EEG) signals in order to translate embedded information about a user's intent into executable commands to control external devices. However, EEG signals are inherently noisy and nonstationary, posing a challenge to extended BCI use. Conventionally, a BCI classifier is trained via supervised learning in an offline calibration session; once trained, the classifier is deployed for online use and is not updated. As the statistics of a user's EEG data change over time, the performance of a static classifier may decline with extended use. It is therefore desirable to automatically adapt the classifier to current data statistics without requiring offline recalibration. In an existing semi-supervised learning approach, the classifier is trained on labeled EEG data and is then updated using incoming unlabeled EEG data and classifier-predicted labels. To reduce the risk of learning from incorrect predictions, a threshold is imposed to exclude unlabeled data with low-confidence label predictions from the expanded training set when retraining the adaptive classifier. In this work, we propose the use of a language model for spelling error correction and disambiguation to provide information about label correctness during semi-supervised learning. Results from simulations with multi-session P300 speller user EEG data demonstrate that our language-guided semi-supervised approach significantly improves spelling accuracy relative to conventional BCI calibration and threshold-based semi-supervised learning.
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http://dx.doi.org/10.1109/smc53654.2022.9945561 | DOI Listing |
Clin EEG Neurosci
January 2025
Palma Sola Neurology Associates, Bradenton, FL, USA.
Evoked potential metrics extracted from an EEG exam can provide novel sources of information regarding brain function. While the P300 occurring around 300 ms post-stimulus has been extensively investigated in relation to mild cognitive impairment (MCI), with decreased amplitude and increased latency, the P200 response has not, particularly in an oddball-stimulus paradigm. This study compares the auditory P200 amplitudes between MCI (28 patients aged 74(8)) and non-MCI, (35 aged 72(4)).
View Article and Find Full Text PDFJ Family Med Prim Care
December 2024
Department of Psychiatry and Behavioral Health, Jersey Shore University Medical Center, Neptune, NJ, USA.
Objective: Selecting the right medication for major depressive disorder (MDD) is challenging, and patients are often on several medications before an effective one is found. Using patient EEG patterns with computer models to select medications is a potential solution, however, it is not widely performed. Therefore, we evaluated a commercially available EEG data analysis system to help guide medication selection in a clinical setting.
View Article and Find Full Text PDFMethodsX
June 2025
Medical College of Wisconsin, Department of Neurosurgery, 8701 Watertown Plank Road, Milwaukee, WI, 53226.
Electrographic recording of brain activity through either surface electrodes (electroencephalography, EEG) or implanted electrodes (electrocorticography, ECOG) are valuable research tools in neuroscience across many disciplines, including epilepsy, sleep science and more. Research techniques to perform recordings in rodents are wide-ranging and often require custom parts that may not be readily available. Moreover, the information required to connect individual components is often limited and can therefore be challenging to implement.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Neurosurgery, Affiliated Hospital of Zunyi Medical University, Dalian Road 149, Huichuan District, Zunyi, 563000, Guizhou Province, China.
The aim of the study was to evaluate the concomitant psychiatric disorders of anxiety and depression in patients with epilepsy caused by low-grade brain tumors (LBTs). We retrospectively reviewed the clinical data of patients who underwent preoperative neuropsychological evaluations of anxiety and depression and subsequent epilepsy surgery for LBTs. The univariate and multivariate analyses were conducted to analyze the risk factors of the occurrence of anxiety and depression.
View Article and Find Full Text PDFBiol Psychiatry Cogn Neurosci Neuroimaging
January 2025
School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou 511442, China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, China; Guangdong Province Key Laboratory of Biomedical Engineering, South China University of Technology, Guangzhou 510006, China; Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai 980-8575, Japan. Electronic address:
Background: The detection of abnormal brain activity plays an important role in the early diagnosis and treatment of major depressive disorder (MDD). Recent studies have shown that the decomposition of the electroencephalography (EEG) spectrum into periodic and aperiodic components is useful for identifying the drivers of electrophysiologic abnormalities and avoiding individual differences.
Methods: This study aimed to elucidate the pathologic changes in individualized periodic and aperiodic activities and their relationships with the symptoms of MDD.
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