The publication of medical articles has become increasingly complex, linked to multiple factors. It poses difficult problems for both authors and journals themselves. This Editorial addresses current and controversial issues: peer review, preprints as a new way of disseminating knowledge, the growing number of publications without peer review and its variants, and the risks of predatory publications. The article proposes future guidelines as an editorial policy of MEDICINA. The controversy continues, and surely the passage of time will place our proposal in a changing scientific world like knowledge itself.
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JBI Evid Synth
January 2025
Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.
Objective: The objective of this scoping review will be to describe existing guidance documents or studies reporting on the conduct of meta-analyses in updated systematic reviews (USRs) or living systematic reviews (LSRs).
Introduction: The rapid increase in the medical literature poses a substantial challenge in keeping systematic reviews up to date. In LSRs, a review is updated with a pre-specified frequency or when some other signalling criterion is triggered.
Chem Biol Interact
January 2025
College of Pharmacy, Yeungnam University, Gyeongsan 38541, Republic of Korea. Electronic address:
Prostate cancer, the second leading cause of cancer-related mortality in men, exhibits distinct metabolic reprogramming involving zinc and citrate metabolism. This study investigated whether targeting this unique metabolic profile could offer an effective therapeutic approach. A series of novel oxindole derivatives were synthesized and evaluated for their inhibitory effects on transcription factors (TFs) and antiproliferative activity across various cancer cell lines.
View Article and Find Full Text PDFLaw Hum Behav
January 2025
Department of Psychiatry and Behavioral Sciences, University of New Mexico Health Sciences Center.
Objective: We conducted a survey to catalog the state of open science in the field of psychology and law. We addressed four major questions: (a) How do psycholegal researchers define open science? (b) How do psycholegal researchers perceive open science? (c) How often do psycholegal researchers use various open science practices? and (d) What barriers, if any, do psycholegal researchers face or expect to face when implementing open science practices?
Hypotheses: We did not make specific hypotheses given the exploratory and descriptive nature of the study.
Method: We surveyed 740 psychology and law researchers (45% faculty, 64% doctoral degree, 66% women, and 85% White/non-Hispanic) about their perceptions of and experiences with open science using a mixed-methods design.
Interact J Med Res
January 2025
Department of Nursing Science, Diagnostics in Healthcare and eHealth, Trier University, Trier, Germany.
Background: Psychoeducation positively influences the psychological components of chronic low back pain (CLBP) in conventional treatments. The digitalization of health care has led to the discussion of virtual reality (VR) interventions. However, CLBP treatments in VR have some limitations due to full immersion.
View Article and Find Full Text PDFBackground: Dupilumab has been added to National Cancer Comprehensive Network (NCCN) guidelines as a therapeutic strategy for managing certain cutaneous immune-related adverse events (cirAEs) from immune checkpoint inhibitor (ICI) therapy. However, little is known about the implications of dupilumab for cancer outcomes in this population. In this multi-institutional study, we evaluate the impact of dupilumab treatment on survival among ICI recipients.
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