AI Article Synopsis
- ALS (amyotrophic lateral sclerosis) is a common and fatal motor neuron disease in adults, with recent research providing new insights after years of challenges and failures in treatment.
- A literature search from January 2016 to June 2022 indicates advancements in early diagnosis, monitoring, and treatment options for ALS.
- Despite its incurable nature, there is growing optimism regarding ALS management and outcomes for patients in the near future.
Article Abstract
Background And Purpose: Amyotrophic lateral sclerosis (ALS) is among the most common motor neuron diseases in adults. Nevertheless, ALS remains fatal, despite decades of research and clinical trials, which has led to negative conclusions until recently in regard to four specific treatments. It is well known that we can learn from failures, and we consider that the time has come to present positive insight on this disease.
Methods: We did a literature search using PubMed and Scopus for articles published in English from 1 January 2016, to 30 June 2022 dealing with "amyotrophic lateral sclerosis", diagnosis, treatment, and biomarkers.
Results: A comprehensive review of the literature on diagnosis, monitoring, and treatment of this condition showed convincing evidence that we are now able to diagnose earlier as well as to better monitor and treat ALS.
Conclusions: Although ALS is often difficult to diagnose and remains incurable, there are many indications that an optimistic view of ALS management in the coming years is now realistic.
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| http://dx.doi.org/10.1111/ene.15738 | DOI Listing |
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