Lensless holographic microscopy (LHM) comes out as a promising label-free technique since it supplies high-quality imaging and adaptive magnification in a lens-free, compact and cost-effective way. Compact sizes and reduced prices of LHMs make them a perfect instrument for point-of-care diagnosis and increase their usability in limited-resource laboratories, remote areas, and poor countries. LHM can provide excellent intensity and phase imaging when the twin image is removed. In that sense, multi-illumination single-holographic-exposure lensless Fresnel (MISHELF) microscopy appears as a single-shot and phase-retrieved imaging technique employing multiple illumination/detection channels and a fast-iterative phase-retrieval algorithm. In this contribution, we review MISHELF microscopy through the description of the principles, the analysis of the performance, the presentation of the microscope prototypes and the inclusion of the main biomedical applications reported so far.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918952PMC
http://dx.doi.org/10.3390/s23031472DOI Listing

Publication Analysis

Top Keywords

mishelf microscopy
12
multi-illumination single-holographic-exposure
8
single-holographic-exposure lensless
8
lensless fresnel
8
fresnel mishelf
8
biomedical applications
8
microscopy
4
microscopy principles
4
principles biomedical
4
applications lensless
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!