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The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy--butyl-calix[4]arenes. | LitMetric

A practical method of selective alkylation of the third hydroxyl group of disubstituted -butyl-calix[4]arenes using anhydrous barium hydroxide as a base was developed in this study. The use of this method in the synthesis of inherently chiral derivatives is shown herein.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921822PMC
http://dx.doi.org/10.3390/molecules28031089DOI Listing

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