AI Article Synopsis
- - During sepsis, the glycocalyx, which is a protective layer on blood vessels, becomes disrupted due to various harmful effects in the body.
- - The thickness of the glycocalyx may indicate how severe the sepsis is, suggesting it could be a promising target for new treatments.
- - This review explores how nutritional and medication strategies could positively impact changes in the glycocalyx during sepsis and the importance of timing for these interventions.
Article Abstract
During sepsis, a combination of pathophysiological insults disrupts the glycocalyx. The thickness of the glycocalyx is correlated with parameters of disease severity, making it a potential new and independent target for therapeutic strategies in sepsis. The aim of this review was to examine potential beneficial effects of nutritional and pharmacological measures on glycocalyx alterations during sepsis and their timing.
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| http://dx.doi.org/10.23736/S0375-9393.22.16834-3 | DOI Listing |
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