A female Hypsugocf.vordermanni was caught at a stream near a village road in Mantailang, Crocker Range Park, Sabah, on 12 November 2018. This bat is a new record for the national park and the second record for Sabah. It was first recorded from Banggi Island, Kudat, in 1991. The species' few records throughout its range is most likely due to sampling effort bias towards forest interior and cave-dwelling species, as this species is more likely an edge-space aerial forager. It is morphologically similar to Peninsular Malaysia's , but the latter has never been reported from Borneo. Therefore, additional specimen collection and molecular data for H.cf.vordermanni are needed for further species confirmation. More information on ecology is also crucial in aiding the management plan for this species as it is currently classified as Data Deficient by the IUCN.
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http://dx.doi.org/10.3897/BDJ.10.e87860 | DOI Listing |
J Chem Phys
December 2024
Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Micron-scale colloidal particles with short-ranged attractions, e.g., colloids functionalized with single-stranded DNA oligomers, have emerged as a powerful platform for studying colloidal self-assembly phenomena with the long-term goal of identifying routes for metamaterial fabrication.
View Article and Find Full Text PDFNMR Biomed
January 2025
Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota, USA.
Ageing is a complex phenomenon affecting a wide range of coexisting biological processes. The homogeneity of the studied population is an essential parameter for valid interpretations of outcomes. The presented study capitalises on the MRI data available in the Human Connectome Project-Aging (HCP-A) and, within individuals over 55 years of age who passed the HCP-A section criteria, compares a subgroup of 37 apparently neurocognitively healthy individuals selected based on stringent criteria with 37 age and sex-matched individuals still representative of typical ageing but who did not pass the stringent definition of neurocognitively healthy.
View Article and Find Full Text PDFMol Cell
January 2025
Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institutes, Stanford University, Stanford, CA 94305, USA. Electronic address:
Although critical for tuning the timing and level of transcription, enhancer communication with distal promoters is not well understood. Here, we bypass the need for sequence-specific transcription factors (TFs) and recruit activators directly using a chimeric array of gRNA oligos to target dCas9 fused to the activator VP64-p65-Rta (CARGO-VPR). We show that this approach achieves effective activator recruitment to arbitrary genomic sites, even those inaccessible when targeted with a single guide.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
January 2025
Department of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH, USA.
Sequential irradiation has been advocated for mitigating the reduction in fatigue properties of tendon compared to a single dose. However, to our knowledge, its capability of mitigating fatigue losses in bone is unknown. Recently, we reported that sequential irradiation did not mitigate losses in high-cycle S-N fatigue life of cortical bone at 15 kGy; however, it is unclear if sequential irradiation provides a benefit to fatigue crack propagation resistance.
View Article and Find Full Text PDFConserv Physiol
November 2024
Department of Biological Sciences, University of the Pacific, 3601 Pacific Ave., Stockton, CA 95211, USA.
Animals in nature potentially experience multiple stressors, and those of anthropogenic origin are likely to be repeated or chronic. However, stress hormone levels are highly context-dependent and are not consistent predictors of chronic stress in wildlife. Profiling the downstream consequences of repeated stress responses, such as changes in metabolism or gene expression, may be more informative for predicting their individual-level health consequences and population-level impacts, which are key objectives for wildlife conservation.
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