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Synergistic Toxicities from Multiple Therapies for Synchronous Malignancies. | LitMetric

Synergistic Toxicities from Multiple Therapies for Synchronous Malignancies.

Case Rep Oncol

Division of General Internal Medicine, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.

Published: February 2023

Patients may present with multiple malignancies in the setting of particular environmental and occupational exposures. These patients often require combination systemic therapy, which has not yet been studied for concurrent use. While toxicities for specific chemotherapies and immunotherapies may be well known, the possibility of exaggerated toxicity due to combination therapy exists and is understudied. Several trials are underway that may shed further light on how combination therapies affect patient toxicity. This case report outlines the unfortunate development of severe edema and rash, refractory to traditional methods of management, from combining immunotherapy and chemotherapy.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903141PMC
http://dx.doi.org/10.1159/000529017DOI Listing

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